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@alenabeauty.bsky.socialOct 11, 2026, 9:10 PM

🧬 Оксидативният стрес – невидимият клетъчен враг!
🔥 Как свободните радикали могат да увреждат клетките и защо антиоксидантният баланс е толкова важен?
alena-beauty.com/oksidativnia...
#OxidativeStress #CellularHealth

@alenabeauty.bsky.socialOct 11, 2026, 9:07 PM

🛡️ Антиоксидантите – как тялото ни се защитава отвътре?
🧬 Свободни радикали, оксидативен стрес и естествени клетъчни механизми. Защо балансът е по-важен от високите дози добавки?
alena-beauty.com/antioksidant...
#Antioxidants #OxidativeStress

@sigtrans-sttt.bsky.socialOct 11, 2026, 3:30 PM

Researchers reveal how #Connexin43-mediated mitochondrial transfer from mesenchymal stem cells activates PGC1α signaling, reducing #OxidativeStress and #Inflammation to improve renal recovery after #Ischemia-reperfusion injury.

#STTT #OpenAccess: doi.org/10.1038/s413...

Connexin 43-dependent mesenchymal stem cell mitochondrial transfer activates PGC1α disrupting oxidative-inflammation axis in ischemia-reperfusion injury
@alicefrolov.bsky.socialOct 6, 2026, 5:00 PM

New visualization: "The oxidative tipping point: ROS output outpaces antioxidant defense across the lifespan"

#RedoxBiology #MitochondrialBioenergetics #OxidativeStress #ReactiveOxygenSpecies #ElectronTransportChain #NRF2Signaling #FreeRadicalBiology

New visualization: "The oxidative tipping point: ROS output outpaces antioxidant defense across the lifespan" Subtitle: Simulated mitochondrial superoxide flux (left) vs enzymatic antioxidant capacity (right) per tissue and age. I am sharing a diverging paired-lollipop balance plot developed to communicate the divergence between mitochondrial reactive oxygen species generation and enzymatic scavenging capacity as a function of chronological age across four representative tissues (myocardium, skeletal muscle, hepatic parenchyma, and cortical neurons). I want to emphasize at the outset that the underlying values are simulated; they are parameterized to reproduce qualitative trends reported in the redox biology literature rather than to represent empirical measurements from a specific cohort. The mirror-lollipop geometry places superoxide flux on the left axis and combined antioxidant capacity (aggregating SOD2, catalase, and glutathione peroxidase activity) on the right, with a shared central baseline. This layout makes the widening asymmetry between the two arms readily interpretable per tissue-age stratum. The left-hand stems model electron leak at Complexes I and III, scaled to reflect the age-associated decline in electron transport chain coupling efficiency and the attendant increase in single-electron reduction of molecular oxygen. The right-hand stems encode declining enzymatic detoxification, incorporating the documented attenuation of NRF2-mediated transcriptional responses with advancing age. The central mechanistic claim rendered by the figure is the crossover point at which ROS output exceeds buffering capacity, initiating a self-amplifying regime of macromolecular oxidation, mtDNA lesion accumulation, and further ETC dysfunction. Post-mitotic tissues (neurons, myocardium) reach this inflection earlier in the simulated trajectory, consistent with their limited mitochondrial turnover.
@molneurodegen.bsky.socialOct 5, 2026, 2:13 PM

#OxidativeStress -induced #microglial CD22 upregulation impairs #phagocytosis and exacerbates #Huntingtons disease

Yan Hua Lee, Jian Jing Siew, Chia-Wei Lee...Takashi Angata & Yijuang Chern

link.springer.com/article/10.1...

@nikkiserenity.bsky.socialSep 30, 2026, 12:42 AM

September is Pain Awareness Month and Echo Water may be able to help! Use my discount code NIKKISERENITY10 @ echowater.com?ref=NIKKISER...
#EchoWater #HydrogenWater #Hydrogen #PainAwareness #PainAwarenessMonth #Recovery #Antioxidants #OxidativeStress #WorkoutRecovery #HydrogenRichWater #Inflammation

@inorgchemfront.rsc.orgSep 28, 2026, 3:14 AM

🔔 Research article by Seongmin Park, Mingeun Kim, Mi Hee Lim 𝘦𝘵 𝘢𝘭.

Reactivities of endocannabinoids toward metal-induced amyloid-β aggregation and oxidative stress associated with Alzheimer's disease

🔗 doi.org/10.1039/d6qi...

#AlzheimersDisease #Endocannabinoids #AmyloidBeta #OxidativeStress

@researchdent-tums.bsky.socialSep 27, 2026, 2:27 PM

What does your saliva say about IVF outcomes? Research suggests that higher antioxidant levels in saliva may correlate with successful treatments. Could this be a game changer? #IVF #OxidativeStress
www.rimpacts.com/rd/p?c=10077... 📄DOI: doi.org/10.1002/hsr2...

@sigtrans-sttt.bsky.socialSep 24, 2026, 12:45 PM

#MultipleOrganDysfunction syndrome involves interconnected inflammation, microcirculatory disruption, coagulation abnormalities, cell death, DNA damage, and #OxidativeStress, creating opportunities for mechanistic and therapeutic research.

#STTT #OpenAccess: doi.org/10.1038/s413...

Multiple organ dysfunction syndrome: molecular mechanisms and therapeutic strategies
@northwell-journals.bsky.socialSep 23, 2026, 4:35 PM

Molecular Medicine - Journal
Article in Press: Oxidative stress and endothelial dysfunction: linking cellular damage to cardiovascular disease and erectile dysfunction | #MolecularMedicine #CVD #ED #OxidativeStress #EndothelialDysfunction link.springer.com/article/10.1...

Fig. 1 Cardiovascular sources of ROS. The primary sources of reactive oxygen species (ROS) in the cardiovascular system include mitochondrial dysfunction, NADPH oxidases (NOX), xanthine oxidase (XO), and uncoupled endothelial nitric oxide synthase (eNOS). A Triggers, such as chronic inflammation and hyperglycemia, cause mitochondrial membrane potential loss, which induces leakage of free radicals like superoxide anions and hydroxyl radicals. B In the presence of xanthine oxidase, hypoxic conditions may also activate the conversion of xanthine and hypoxanthine to uric acid, which is a potent pro-oxidant. C In addition, inflammatory mediators activates NADPH oxidases (NOX) to produce free radicals. D Under pathological conditions, such as dyslipidaemia or renal impairment, eNOS becomes uncoupled and produce superoxide instead of nitric oxide, in the presence of cofactors like as tetrahydrobiopterin (BH4). (E) Metabolic and inflammatory pathological amplifiers, such as diabetes and ......
@biomedicines.bsky.socialSep 21, 2026, 5:14 AM

⚡🧬 Mitochondrial health and ROS balance are critical for cardiomyocyte survival. This study identifies the ABA/LANCL1-2 system as a regulator of oxidative stress responses and mitochondrial resilience in cardiac cells. #Mitochondria #OxidativeStress
www.mdpi.com/2227-9059/12...

@biomedicines.bsky.socialSep 21, 2026, 1:48 AM

🧬 Could oxidative stress hold the key to better oral cancer care? This review explores ROS-driven OSCC progression, promising biomarkers for early detection, and melatonin as a potential adjunct therapy. 🔬 #OralCancer #OxidativeStress
mdpi.com/2227-9059/12...

@sigtrans-sttt.bsky.socialSep 20, 2026, 6:00 AM

How does #HCC withstand #OxidativeStress during therapy?

This study identifies a HIF1α–KLF4–hemoglobin axis that scavenges ROS and promotes sorafenib resistance, revealing a targetable redox adaptation.

#STTT #OpenAccess: doi.org/10.1038/s413...

#TumorHypoxia #TherapyResistance #CancerBiology

HIF1α-KLF4 signaling dictates extra-erythrocyte expression of hemoglobin conferring sorafenib resistance in hepatocellular carcinoma
@sigtrans-sttt.bsky.socialSep 18, 2026, 3:30 PM

This review maps viral oncogenesis from host-cell transformation and genomic instability to immune suppression and chronic #inflammation, connecting these mechanisms with evolving strategies to prevent and treat virus-related cancers.

#STTT #OpenAccess: doi.org/10.1038/s413...

#OxidativeStress

Viral oncogenesis in cancer: from mechanisms to therapeutics
@sigtrans-sttt.bsky.socialSep 16, 2026, 7:00 AM

SMG1 and DNA-PK phosphorylate NRF2 under mild #OxidativeStress, weakening KEAP1 binding and activating #Antioxidant programs that suppress #Ferroptosis, revealing a redox stress–intensity-dependent switch in #Cancer cell fate.

#STTT #OpenAccess: doi.org/10.1038/s413...

Two stress-responsive kinases suppress ferroptosis by activating antioxidant programs under mild oxidative stress
@viennaairwaylab.bsky.socialSep 15, 2026, 3:56 AM

Olfactory mucosa biopsies from people with MCI and Alzheimer’s have early mitochondrial and NRF2-related oxidative-stress changes tied to poorer odor identification, suggesting smell-based molecular signs could help flag early Alzheimer’s risk.
#OxidativeStress #NRF2 #Rhinology
🔗 ino.to/rxOY1Fs

@genesndiseases.bsky.socialSep 14, 2026, 1:05 PM

Promising therapies need stronger clinical evidence.
This review explains how autologous ozonized blood transfusion reduces #OxidativeStress and #inflammation while highlighting barriers to wider adoption. #NRF2 #NFκB
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

@biomedicines.bsky.socialSep 14, 2026, 12:52 AM

🧪 Could methylglyoxal be driving diabetic bladder dysfunction? This review explores the MGO–AGEs–RAGE–ROS pathway and potential therapies, including metformin and polyphenols, to protect bladder function. 💡 #Diabetes #OxidativeStress
mdpi.com/2227-9059/12...

@sigtrans-sttt.bsky.socialSep 12, 2026, 4:01 PM

#OxidativeStress and #Inflammation contribute to #Ischemia-reperfusion kidney injury.

This study shows that Cx43-mediated mitochondrial transfer from BM-MSCs activates PGC1α, restoring #MitochondrialHomeostasis and renal function.

#STTT #OpenAccess: doi.org/10.1038/s413...

Connexin 43-dependent mesenchymal stem cell mitochondrial transfer activates PGC1α disrupting oxidative-inflammation axis in ischemia-reperfusion injury
@beyondpesticides.orgSep 11, 2026, 4:01 PM

A review of #environmental #pollutants featured in Antioxidants analyzes how different compounds, including #pesticides, amplify #oxidativestress, an imbalance between production of reactive oxygen species and the body’s ability to detoxify them. #ros #health ➡️ Daily News: https://ow.ly/3ZV650ZMC96

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