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@inorgchemfront.rsc.org Sep 28, 2026, 3:14 AM

🔔 Research article by Seongmin Park, Mingeun Kim, Mi Hee Lim 𝘦𝘵 𝘢𝘭.

Reactivities of endocannabinoids toward metal-induced amyloid-β aggregation and oxidative stress associated with Alzheimer's disease

🔗 doi.org/10.1039/d6qi...

#AlzheimersDisease #Endocannabinoids #AmyloidBeta #OxidativeStress

@scienceinseattle.com Sep 18, 2026, 4:32 PM

Drs. David Marcus and Michael Bruchas at @uwmedicine.bsky.social identified how naturally occurring brain chemicals called #endocannabinoids help regulate the drive to pursue rewards.

🧠 The data could help clarify how brain systems involved in motivation become disrupted: https://bit.ly/4huZzLZ

@karl-theodor.mastodon.social.ap.brid.gy Sep 16, 2026, 10:21 AM

Human #EndocannabinoidSystem

In the 1990’s, scientists discovered endocannabinoids, the natural cannabis-like molecules produced by the #humanbody. #Scientists began to realize #cannabis exerted its effects, in part, by mimicking our #endocannabinoids. It […]

[Original post on mastodon.social]

Research initially suggested endocannabinoid receptors were only present in the brain and nerves, but scientists later found that the receptors are present throughout the body, including our skin, immune cells, bone, fat tissue, liver, pancreas, skeletal muscle, heart, blood vessels, kidney, and gastrointestinal tract.3 We now know the endocannabinoid system is involved in a wide variety of processes, including pain, memory, mood, appetite, stress, sleep, metabolism, immune function, and reproductive function.4,5 Endocannabinoids are arguably one of the most widespread and versatile signaling molecules known to man.

References

1. De Laurentiis A, Araujo HA, Rettori V. Role of the endocannabinoid system in the neuroendocrine responses to inflammation. Curr Pharm Des. 2014;20(29):4697-4706.

2. McPartland JM, Matias I, Di Marzo V, Glass M. Evolutionary origins of the endocannabinoid system. Gene. 2006;370:64-74.doi:https://doi.org/10.1016/j.gene.2005.11.004.

3. Mackie K. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol. 2008;20 Suppl 1:10-14. doi:10.1111/j.1365-2826.2008.01671.x.

4. Alger BE. Getting High on the Endocannabinoid System. Cerebrum Dana Forum Brain Sci. 2013;2013.

5. Maccarrone M, Bab I, Bíró T, et al. Endocannabinoid signaling at the periphery: 50 years after THC. Trends Pharmacol Sci. 2015;36(5):277-296.doi:10.1016/j.tips.2015.02.008.

https://cannabis.semel.ucla.edu/endocannabinoid/

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