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@currentmedscience.bsky.socialSep 10, 2026, 12:30 PM

Why is #CD44v6 exciting in AML?

#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky

Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology

CD44v6 CAR-T Cells Target DNMT3A-Mutant AML: Synergistic Enhancement by Decitabine
@currentmedscience.bsky.socialSep 9, 2026, 2:45 PM

Elevated #S100A8/A9 drives abnormal #proliferation, migration, #adhesion & #Chemoresistance in #DNMT3A mutant AML. Targeting this pathway could be a promising therapeutic strategy. #medsky

Read more: doi.org/10.1007/s115...

#currentmedicalscience #Oncology #CancerTherapeutics

Targeting Calprotectin S100A8/A9 to Overcome AML Progression in DNMT3A-Mutant Cells
@currentmedscience.bsky.socialSep 9, 2026, 3:15 AM

A detailed toxicity profile of SG drugs is revealed through #ClinicalTrial data & FRAES/DDInter, uncovering new adverse reactions & drug interactions, advancing #Pharmacovigilance. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Pharmacology #Toxicology #DrugSafety

Toxicities Associated with Sacituzumab Govitecan: Data from Clinical Trials and a Real-World Pharmacovigilance Database
@currentmedscience.bsky.socialSep 8, 2026, 1:02 PM

#Computational data clarify how SZKJT activates #Phytochemicals to treat OSCC. This study provides mechanistic insights into phytochemical-based #CancerTherapy. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Oncology #TranslationalOncology #Phytotherapy #Cancer

Integrative Network Pharmacology and Molecular Docking Analyses on the Mechanisms of San-Zhong-Kui-Jian-Tang in Treating Oral Squamous Cell Carcinoma
@currentmedscience.bsky.socialSep 7, 2026, 2:15 PM

This review explores how #AerobicExercise reshapes molecular pathways, highlighting it as a #Nonpharmacological intervention with broad medical applications. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Neurobiology #ExerciseScience #AnxietyResearch #anxiety

Unraveling the Molecular Underpinnings: The Therapeutic Impact of Aerobic Exercise on Anxiety Disorders
@currentmedscience.bsky.socialSep 6, 2026, 1:45 PM

Study reveals #cardioprotective role of ANP in #ReperfusionInjury.

ANP reduces #myocardial I/R injury by modulating Zn²⁺ homeostasis — pointing to new therapeutic strategies in #CVD. #medsky

To read: doi.org/10.1007/s115...

#currentmedicalscience #Cardiology #TherapeuticTargets

ANP Increases Zn2⁺ Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts
@currentmedscience.bsky.socialSep 5, 2026, 1:15 PM

#PeriodontalDisease causes #BoneLoss & #Inflammation.

Study shows GSK J4 attenuates these effects by targeting #JMJD3 — highlighting #epigenetic modulation as a promising therapeutic strategy. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Dentistry #OralSurgery

@currentmedscience.bsky.socialSep 4, 2026, 2:30 PM

#Celegans is advancing #VirusHostInteraction research.

From #Antiviral #RNAi & #InnateImmune responses to #ReverseGenetics for Orsay virus, #nematodes provide a simple yet powerful model. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Virology #ModelOrganisms

@currentmedscience.bsky.socialSep 3, 2026, 1:00 PM

#ALOX5 is a reliable diagnostic marker in #DKD, linked to immunity and #Ferroptosis. This strengthens prospects for precision #Diagnostics and patient care. #medsky

Know more: doi.org/10.1007/s115...

#currentmedicalscience #Nephrology #Biomarkers #ClinicalResearch