You Wu and David J. Reiner @tamu.bsky.social provide in vivo evidence for the long-proposed role of the Ras effector Ral, a small #GTPase, in regulating the metazoan #exocyst complex. rupress.org/jcb/article/...

#Celegans #Development #Trafficking

You Wu and David J. Reiner @tamu.bsky.social provide in vivo evidence for the long-proposed role of the Ras effector Ral, a small #GTPase, in regulating the metazoan #exocyst complex. rupress.org/jcb/article/...

#Celegans #Development #Trafficking

Loss of periactive-zone scaffold proteins does not enhance neurotransmission defects in cla-1(ΔL) mutants #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #InteractionData #Un https://micropublication.org/journals/biology/micropub-biology-002331

🪱 Read the latest behavior study in #GENETICS where @isabelbeets.bsky.social
and the team investigate how the #Celegans promiscuous RFamide-peptide FLP-14 and its receptors modulate a circuit for oxygen-evoked locomotory arousal.

🔗 buff.ly/uaRNa5E

Chromosome-Scale Assembly of Novel Caenorhabditis sp. 65 (strain JU4118) #micropublication #biology #data #caltechlibrary #Celegans #GenomeAnnouncements #NewFinding https://micropublication.org/journals/biology/micropub-biology-002448

Loss of the Orphan GPCR srd-44 Does Not Alter Chemotaxis of Caenorhabditis elegans to Carolina Mantle Slug Mucus #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NegativeResu https://micropublication.org/journals/biology/micropub-biology-002287

Identification of GEI-14 as a candidate pro-crossover factor by TurboID in C. elegans #micropublication #biology #data #caltechlibrary #Celegans #InteractionData #NewFinding https://micropublication.org/journals/biology/micropub-biology-002380

🪱 Read the latest work from @barrlab.bsky.social in #GENETICS that describes a #Celegans pipeline for mechanistic classification of conserved Autosomal dominant polycystic kidney disease (ADPKD) associated missense variants.

🔗 buff.ly/R2nrikZ

Position available to work on Alternating Hemiplegia of Childhood; develop assays & test compounds using Hart lab #Celegans disease models. Ideal for scientist with Bachelors or Masters degree seeking mentorship, but previous at-the-bench experience is required. See REQ211438 on Brown Univ website.

It's always humbling to talk about what basic science can teach us about ourselves with people outside my usual circle of scientists. Thanks to the Livelong Women's Health Summit for having me on this past weekend's roundtable.
#basicscience #celegans

Analysis of mechanical lysis paradigms for Caenorhabditis elegans protein extraction #micropublication #biology #data #caltechlibrary #Celegans #Methods #Methodology https://micropublication.org/journals/biology/micropub-biology-002356

Role of vitellogenins on the mitochondrial unfolded protein response #micropublication #biology #data #caltechlibrary #Celegans #GeneModel #NewFinding https://micropublication.org/journals/biology/micropub-biology-002360

Cationic amphiphilic drugs (CADs) can disrupt lysosomal function. Peter Roy &co show that a xenobiotic module couples CYP-35B–mediated CAD catabolism to efflux in #Celegans, possibly to #detoxify natural products generated by microbes in the soil 🧪 buff.ly/4BFpg7V

The CCT chaperonin is a context-dependent regulator of RNA-binding protein phase transitions #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding https://micropublication.org/journals/biology/micropub-biology-002420

#celegans to reach the people of the worm

Endogenous Expression of the Class I Phosphatidylinositol Transfer Protein PPIT-2 in Caenorhabditis elegans  #micropublication #biology #data #caltechlibrary #Celegans #ExpressionData #NewFinding https://micropublication.org/journals/biology/micropub-biology-002386

Cationic amphiphilic drugs (CADs) can disrupt lysosomal function. Peter Roy &co show that a xenobiotic module couples CYP-35B–mediated CAD catabolism to efflux in #Celegans, possibly to #detoxify natural products generated by microbes in the soil 🧪 buff.ly/4BFpg7V

Purine salvage enzymes are innate immune regulators in Caenorhabditis briggsae and Caenorhabditis remanei #micropublication #biology #data #caltechlibrary #Celegans #Caenorhabditisbriggsae #Caenorhabd https://micropublication.org/journals/biology/micropub-biology-002371

🪱 Using a CRISPR-based, cell-specific degradation approach, Amezquita et al. demonstrate that the Integrin-Talin axis functions cell-autonomously in #Celegans mechanosensory neurons to regulate presynaptic branch formation.

📖 more in #G3journal 🔗 buff.ly/328B9hw

Semaglutide Reduces Odorant-Driven Chemotaxis and Reproductive Output in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #UndergraduateResearchExperience #PhenotypeDa https://micropublication.org/journals/biology/micropub-biology-002168