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@plosbiology.orgOct 10, 2026, 12:05 PM

What are the #epigenetic mechanisms regulating cellular proteostasis? This study shows that a subunit of the COMPASS histone methyltransferase complex controls ultradian proteostasis gene expression through methylation at #proteostasis gene promoters.
🧪 #AcademicSky
plos.io/4emgONz

This research article is titled "The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics," by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michael J Jurczak, Silvia Liu, Bokai Zhu
@sigtrans-sttt.bsky.socialOct 9, 2026, 12:45 PM

This review links genomic and #Epigenetic changes, metabolic adaptation, immune escape, and therapy-driven selection to emerging evolution-guided strategies for #PrecisionOncology. @fudan-university.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...
#CancerStemness

Tumor evolution: signaling pathways, molecular mechanisms and therapeutic targets
@epigenometech.bsky.socialOct 9, 2026, 12:07 PM

Epigenetics Preprint – Single-Nucleus Multi-Omic Atlas Maps Regulatory Architecture and Non-Coding Variant Effects across Adult Human Tissues www.biorxiv.org/content/10.6...

#Epigenetic #Preprint #SingleCell #MultiOmic
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Perfect for cancer, immunology, and aging research; epigenometech.com

@plosbiology.orgOct 9, 2026, 8:05 AM

What are the #epigenetic mechanisms regulating cellular proteostasis? This study shows that a subunit of the COMPASS histone methyltransferase complex controls ultradian proteostasis gene expression through methylation at #proteostasis gene promoters.
🧪 #AcademicSky
plos.io/4emgONz

This research article is titled "The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics," by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michael J Jurczak, Silvia Liu, Bokai Zhu
@epivinf.bsky.socialOct 7, 2026, 3:29 PM

🙌 Wrapping up the first day of the GA in Malta where our partner @omniscope.bsky.social is based!

👏 Discussions, collaboration and new ideas to advance our work on #epigenetic regulation, #HIV and #LongCOVID

@irsicaixa.es @fundaciolluita.bsky.social @irta-cresa.bsky.social @uni-saarland.de

@letimarchetti.bsky.socialOct 6, 2026, 3:21 PM

Don’t miss the opportunity to join this incredible group of individuals working together to further our understanding of #epigenetic mechanisms in #bloodmalignancies at @nucancer.bsky.social @newcastleuni.bsky.social 🧬🔬 tech job funded by @cancerresearchuk.org - more info at the link bit.ly/3VOQipJ

@jprecmed.bsky.socialOct 6, 2026, 3:03 PM

Are #epigenetic clocks evolving beyond biological age? ⌛️⏰️

New research shows second- and third-generation clocks outperform earlier models for disease prediction, while changes over time add valuable insight into mortality risk.

Read the #Editorial by Neil Panchal 👇️
doi.org/10.1016/j.pr...

@sigtrans-sttt.bsky.socialSep 24, 2026, 4:41 AM

#Aging and #Cancer converge through metabolism, genome maintenance, inflammation, and #Epigenetic regulation. This review examines shared mechanisms, druggable targets, and opportunities for integrated therapies.
#STTT #OpenAccess: doi.org/10.1038/s413...

Aging and cancer: current understandings and future perspectives
@sigtrans-sttt.bsky.socialSep 22, 2026, 7:15 AM

Protein #Lactylation connects cellular metabolism with #Epigenetic regulation.
This review examines its molecular machinery and functions across physiology and disease, highlighting #Biomarker and therapeutic potential.

#STTT #OpenAccess: doi.org/10.1038/s413...

Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications
@genesndiseases.bsky.socialSep 21, 2026, 3:07 PM

How does the #nucleolus shape early development?
This review explores its remodeling in oocytes and embryos, highlighting roles in chromatin organization, #epigenetic inheritance, oocyte maturation and #EmbryonicDevelopment.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...

@boblivion.bsky.socialSep 21, 2026, 1:18 PM

#quotes #books #booksky #excerpts #citations #evolutioninfourdimensions #jablonka #lamb #zeligowski #evolution #epigenetic #genome #dna #mutation #crispr #bacteria #virus #repeat #fragment #defense

@kundakoviclab.bsky.socialSep 21, 2026, 6:52 AM

Looking forward to speaking at " #Epigenetic Regulation of Acquired Behaviors in Health & Disease" workshop next week in Baeza, Spain, organized by Li-Huei Tsai & @barcolab.bsky.social as part of the Biomedicine Workshops of the Universidad Internacional de Andalucía. My 1st visit to Andalusia! ❤️

@natmed.nature.comSep 17, 2026, 10:46 AM

⚡ Our September issue is live! Featuring new research on #epigenetic clocks, #measles transmission, #preeclampsia, #AI for retinal disease diagnosis, #iPSCs for heart failure and much more including Reviews, News and Opinion.
Read it here:

@ahgeditor.bsky.socialSep 15, 2026, 2:07 PM

An Early View: A two-sample Mendelian randomisation study using publicly available GWAS summary statistics evaluates the associations of leukocyte #telomere length and #epigenetic age acceleration with #healthspan.

🔗 Read here: onlinelibrary.wiley.com/doi/full/10....

Figure. 2

Forest plot of MR estimates for genetically proxied LTL and healthspan. The forest plots summarize MR estimates for the associations between LTL and healthspan. Four MR methods were used: IVW, weighted median, weighted mode, and MR Egger regression. Each method is represented by a point estimate, a 95% CI, and the corresponding p-value. CI, confidence interval; IEAA, intrinsic epigenetic age acceleration; IVW, inverse-variance weighted; LTL, leukocyte telomere length; MR, Mendelian randomization; SNP, single-nucleotide polymorphism.
@sproullab.bsky.socialSep 14, 2026, 1:51 PM

🚨 #Postdoc position open.

Want to understand non-canonical #epigenetic regulation of mammalian transcription? Come work @uoe-igc.bsky.social in Edinburgh!

We’re looking for a motivated & collaborative colleague with a strong track record.

📅 14 October 2026
📢 Please share

Apply here 👇

@epigenometech.bsky.socialSep 7, 2026, 3:29 PM

Epigenetics Update - Regulatory mechanisms of maternal imprinting at the murine Dlk1-Dio3 domain u.epigenome.us/m50J3kHD

Ariella Weinberg-Shukron & Anne C. Ferguson-Smith (geneticscam.bsky.social) in Nat Commun

#Epigenetic #Imprinting #DNAm #Dlk1Dio3
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Empower your research at epigenometech.com

@epigenometech.bsky.socialSep 7, 2026, 11:24 AM

Epigenetics Update - Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming u.epigenome.us/Cd93guNv

Yonatan Stelzer (weizmann.ac.il) in natcomms.nature.com

#Epigenetic #Imprinting #DNAm #Dlk1Dio3
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epigenometech.com

@currentmedscience.bsky.socialSep 5, 2026, 1:15 PM

#PeriodontalDisease causes #BoneLoss & #Inflammation.

Study shows GSK J4 attenuates these effects by targeting #JMJD3 — highlighting #epigenetic modulation as a promising therapeutic strategy. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Dentistry #OralSurgery