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@jdevos.bsky.socialSep 28, 2026, 11:37 AM

China tests CAR-T therapies faster than the rest of the world but regulatory changes could slow them down.
#CARTCells

buff.ly/Dioelh7

@imtadvances.bsky.socialSep 15, 2026, 12:20 PM

This review explores the bottom-up development of LGR5-targeting immunotherapeutics, showing how a highly specific α‑LGR5 antibody can be adapted into multiple modalities

📖 Read more: vist.ly/5ihju

#Immunotherapy #CancerResearch #CARTcells #PrecisionMedicine #OpenAccess

Wnt pathway illustration with modulation by RSPO showing gene expression changes.
@jdevos.bsky.socialSep 15, 2026, 10:30 AM

Early but promising results with armored #CARTcells targeting glypican-3 and co-expressing IL-15 and IL-21 in pediatric hepatoblastoma. Step by step, CAR-T cells are beginning to make solid tumors addressable.

buff.ly/ZqJ8UbH

@currentmedscience.bsky.socialSep 10, 2026, 12:30 PM

Why is #CD44v6 exciting in AML?

#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky

Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology

CD44v6 CAR-T Cells Target DNMT3A-Mutant AML: Synergistic Enhancement by Decitabine
@jem.orgSep 10, 2026, 12:01 AM

Intravesical mesothelin-based #CARTcells targeting MUC16 effectively control #BladderCancer in preclinical models. From Parwiz Abrahimi, Renier Brentjens, Jedd Wolchok, Taha Merghoub et al.: rupress.org/jem/article/...

Part of our #CancerImmunotherapy 2026
👉 rupress.org/jem/collecti...
#CSHAsia