@currentmedscience.bsky.socialEarly-onset #diabetes across generations may have a genetic basis.
This study identifies #PathogenicVariants in HNF1A, PDX1, KCNJ11 and WFS1, supporting precision diagnosis and treatment.
#currentmedicalscience: doi.org/10.1007/s115...
@currentmedscience.bsky.socialCould early recognition prevent vision loss from #OcularToxoplasmosis?
This study highlights #retinochoroiditis as the main presentation and the value of timely testing and treatment to reduce recurrence.
#currentmedicalscience: doi.org/10.1007/s115...
@currentmedscience.bsky.socialA simple metabolic marker may signal heart risk.
This study links greater #InsulinResistance to a higher 10-year risk of #CardiovascularDisease, highlighting metabolic health as an important predictor of future heart events.
@currentmedscience.bsky.social#Hypoxia makes liver cancer harder to treat.
This study shows that 3-BrPA enhances arterial #embolization, suppressing tumor growth and promoting necrosis, offering a strategy to overcome hypoxic resistance.
#currentmedicalscience: doi.org/10.1007/s115...
@currentmedscience.bsky.socialDefining predictive tools reshapes orthopedic surgery.
Dual stream attention networks predict #TibialPlateauFractures classifications with accuracy, automating assessment & supporting surgical planning. #medsky
Read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialElevated NCAPD3 expression drives #HCC #metastasis. Inhibition impedes tumor growth and metastatic potential by blocking PI3K–AKT signaling, underscoring translational promise in #Oncology #medsky
Full article: doi.org/10.1007/s115...
@currentmedscience.bsky.socialGBDT, integrated with APACHE II, strengthens mortality prediction in acute #Gastrointestinal bleeding patients, delivering reliable prognostic insights for clinical decision support. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#Vitamin D activates Nrf2/HO-1 pathway to alleviate inflammation and injury after acute #CerebralInfarction, highlighting Nrf2’s role and VD’s therapeutic potential in #IschemicStroke. #medsky
Learn more: doi.org/10.1007/s115...
@currentmedscience.bsky.socialThis study highlights a DNN model that significantly improves #ParkinsonsDisease diagnosis accuracy using spiral & wave handwriting, outperforming ML/DL models & advancing future diagnostics. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Neurotechnology#MachineLearning
@currentmedscience.bsky.socialFindings underscore the critical need for targeted interventions in severe pediatric #MentalDisorders. Early detection & management are essential to mitigate long-term developmental impacts. #medsky
Read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#Bcl2 family proteins regulate cell survival and death, with roles spanning autophagy, calcium #homeostasis, and mitochondrial dynamics, offering therapeutic promise through BH3 mimetics. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialCan #Microglia hold the key to stroke defense?
Casr-related neuroprotection induced by ischemic preconditioning is linked to M2 microglial transformation, offering insight into #IschemicStroke defense. #medsky
Read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialFindings show #PPA1 interacts with FUS to prevent mitochondrial mislocalization, preserving mitochondrial function & promoting adipose browning, highlighting its therapeutic potential in #MetabolicDisorders. #medsky
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#currentmedicalscience #Metabolism
@currentmedscience.bsky.social#UTROSCTs: rare uterine tumors with uncertain malignant potential. This study combines a literature review and 8 cases revealing novel markers and long term disease free outcomes. #medsky
Full article: doi.org/10.1007/s115...
@currentmedscience.bsky.socialHow does konjac oligosaccharide (KOS) improve gut motility?
By activating the 5 HT4R/cAMP/PKA/p CREB pathway, KOS improves loperamide-induced #constipation, enhancing #IntestinalMotility. #medsky
Read here: doi.org/10.1007/s115...
@currentmedscience.bsky.social#Epigenetics offers new hope for #SNHL.
This review explores #histone modifications, #DNAMethylation & ncRNAs in hair cell damage, highlighting small‑molecule compounds as promising therapies for SNHL. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#WorldHeartDay | September 29, 2026
#CardiovascularDisease remains a research priority, advancing prevention, early diagnosis, and #TranslationalMedicine.
#CurrentMedicalScience publishes peer-reviewed #cardiovascularresearch and clinical innovation.
Explore recent articles: t.co/5LdKznXcNc
@currentmedscience.bsky.socialThis study reveals that #Electroacupuncture activates GDNF/GFRα1/PI3K/Akt signaling, increases enteric glial cells, and improves gastrointestinal motility in #FunctionalDyspepsia. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#mRNAVaccines hold promise in #Oncology.
This review highlights RNA design, lipid nanoparticle delivery, antigen encoding, and immunomodulators as strategies to overcome TME barriers in cancer #immunotherapy. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialBy analyzing #CD8+, CD4+, NKT, and γδ T cells, this study underscores the promise of TCR‑T, #CART, and checkpoint inhibitors in achieving long‑term AML control and advancing future therapeutic strategies. #medsky
To read: doi.org/10.1007/s115...
