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@genesndiseases.bsky.socialSep 18, 2026, 12:30 AM

Harnessing transporter biology requires a unified view of #MFSD proteins.
This review consolidates their diverse roles in lipid transport, neurodevelopment, and cancer, positioning them as promising #TherapeuticTargets.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

@sigtrans-sttt.bsky.socialSep 13, 2026, 6:30 AM

Metastatic organotropism shapes #LungAdenocarcinoma progression.
This study identifies tumor, immune and stromal signatures associated with organ-specific #Metastasis, highlighting #Biomarkers and #TherapeuticTargets.

#STTT #OpenAccess: doi.org/10.1038/s413...

Mechanisms and therapeutic targets in distant metastasis of lung adenocarcinoma
@sigtrans-sttt.bsky.socialSep 11, 2026, 10:12 AM

Can #Disulfidptosis reveal new therapeutic vulnerabilities?

This review examines how NADPH depletion and disulfide stress trigger actin cytoskeleton collapse via the Rac–WRC–Arp2/3 pathway and explores emerging #TherapeuticTargets.

#STTT #OpenAccess: doi.org/10.1038/s413...

Disulfidptosis: molecular mechanisms and therapeutic targets
@sigtrans-sttt.bsky.socialSep 11, 2026, 10:04 AM

Tumor-infiltrating B cells could reshape #Cancer #Immunotherapy.

This review explores their diverse subtypes, tertiary lymphoid structures, signaling and crosstalk, and emerging B-cell checkpoints and #TherapeuticTargets.

#STTT #OpenAccess: doi.org/10.1038/s413...

B cells in cancer: functions, mechanisms and therapeutic advances
@currentmedscience.bsky.socialSep 6, 2026, 1:45 PM

Study reveals #cardioprotective role of ANP in #ReperfusionInjury.

ANP reduces #myocardial I/R injury by modulating Zn²⁺ homeostasis — pointing to new therapeutic strategies in #CVD. #medsky

To read: doi.org/10.1007/s115...

#currentmedicalscience #Cardiology #TherapeuticTargets

ANP Increases Zn2⁺ Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts