Among patients with #GastricCancer and positive peritoneal lavage cytology or localized peritoneal metastasis, #chemotherapy plus #gastrectomy was associated with better survival than gastrectomy alone or chemotherapy alone.

Among patients with #GastricCancer and positive peritoneal lavage cytology or localized peritoneal metastasis, #chemotherapy plus #gastrectomy was associated with better survival than gastrectomy alone or chemotherapy alone.
ENO1 connects #Glycolysis with #GastricCancer stemness by regulating ATP pools and lactate homeostasis, which coordinate AMPK/mTOR and PI3K/AKT signaling to promote EMT, self-renewal, migration, and invasion.
Among patients with #GastricCancer and positive peritoneal lavage cytology or localized peritoneal metastasis, #chemotherapy plus #gastrectomy was associated with better survival than gastrectomy alone or chemotherapy alone.
First patient enrolled in COMPASSION-37, Akeso's global Phase 3 of cadonilimab in first-line HER2-negative gastric cancer. Comparator: chemotherapy with or without nivolumab.
#GastricCancer #Biotech #Oncology
Disclaimer: This is NOT a financial advice
Guilford breaks down clinical management of hereditary diffuse #gastriccancer which is intense. Patients often have their stomachs removed, which comes w/ many adverse effects (& a few bennies, he noted, tongue firmly in cheek). #ILCSymposium #HDGC #lobmob #bcsm
Keynote speaker Dr. Parry Guilford breaks down the similarities between #lobular #breastcancer and diffuse #gastriccancer via a hereditary #CDH1 mutation. #ILCSymposium. Good to know as we enter Hereditary Cancer Awareness Week! #bcsm @lobularbca.bsky.social
Mitochondrial redox balance could reveal new cancer clues.
This pan-cancer study links SLC25A39 to tumor progression, immune checkpoints and #immunotherapy response, highlighting its #biomarker potential. #GastricCancer
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Could metal nanoparticles overcome the limitations holding back early #GastricCancer detection?
#MetalNanoparticles (MNPs) paired with imaging, biosensors, liquid biopsy and #AI could boost biomarker detection and diagnostic accuracy.
Ferronova's MAGMAP Trial Shows Promise for Gastric Cancer Treatment with Lymph Node Mapping #Australia #Kyoto #Ferronova #GastricCancer #MAGMAP
#GastricCancer #HemOnc #BoardPrep Boards coming up? 1,500+ board-style hem/onc questions and AI study tools for fellows at Meducation AI. Free 7-day trial: meducationai.com
Gastric cancer advances outlined:
🔬 7.7% cancer deaths worldwide
🔬 69% cases in Asia, high incidence in minorities
🔬 5-year survival varies, 36.4% overall
🔬 HER2 and PD-L1 testing in metastatic cases
#GastricCancer #Oncology #Immunotherapy https://tnyp.me/mkzMBbpw/s
Could perioperative immunotherapy finally change the standard in resectable gastric cancer?
MATTERHORN showed that adding durvalumab to FLOT improved overall survival, with benefit extending across pCR, EFS and OS.
Molecular Medicine - Journal
Article in Press: HEATR1 deficiency enhanced gastric cancer cell PANoptosis to boost anti-tumor immunity | #MolecularMedicine #GastricCancer #PANoptosis #HEATR1 #ImmuneCheckpointInhibitor link.springer.com/article/10.1...
PD-L1 expression and survival in unresectable/recurrent #GastricCancer treated by 1st-line treatment without immune checkpoint inhibitors: JCOG1013A1. www.nature.com/articles/s41...
#GIT
WGCNA and machine learning identify CDRT15P1 as candidate hub gene in gastric adenocarcinoma; knockdown affects proliferation, migration, and invasion, implicating proteasome pathways.
Details: https://www.maxapress.com/article/doi/10.48130/git-0026-0011
#GastricCancer #HubGenes #CDRT15P1