@isdb.bsky.social
ISDB is a non-profit scientific association that promotes the study of developmental biology
@amartinezarias.bsky.socialReposted by @isdb.bsky.socialAn aptly titled paper shows, for the first time, the significance of heterogeneities of gene expression in the construction of complex systems : fate decisions are group decisions. Previously @biorxivpreprint
cell.com/cell/fulltex... #MustRead #Gastruloids
@Jshendure lab
@mirlab.bsky.socialReposted by @isdb.bsky.social1/ Our paper, “Enhancer binding kinetics explain transcription factor hub formation,” is now published! Here we set out to understand why transcription factors form bright clusters or “hubs” in the nucleus, and whether those hubs actually control gene activity.
tinyurl.com/38uf8348
@isdb.bsky.socialReposted by @isdb.bsky.socialHappy #FluorescenceFriday. This video shows a group of neural crest cells (🟣) remodelling a mesh of fibronectin matrix (🔵). This is part of a biorxiv paper showing the reciprocal relationship between NC and neural tube morphogenesis.
📹: Kai Weißenbruch, UCL
👇👇👇
www.biorxiv.org/content/10.6...
@cellsdev.bsky.socialReposted by @isdb.bsky.social#Macrophages are mechanosensitive cells. They respond to mechanical signalling from the surrounding tissue, such as during fibrosis. In this review, the authors discuss the significance of the macrophage-fibroblast communication in a profibrotic niche. #immune
👇
www.sciencedirect.com/science/arti...
@isdb.bsky.socialHappy #FluorescenceFriday. This video shows a group of neural crest cells (🟣) remodelling a mesh of fibronectin matrix (🔵). This is part of a biorxiv paper showing the reciprocal relationship between NC and neural tube morphogenesis.
📹: Kai Weißenbruch, UCL
👇👇👇
www.biorxiv.org/content/10.6...
@hannamariahakkinen.bsky.socialReposted by @isdb.bsky.socialHow do long-lived multipotent stem cells cope with mechanical stress in vivo?
We found that neural crest cells are protected from mechanical stress during migration in confined tissue environment.
www.nature.com/articles/s41...
@isdb.bsky.socialReposted by @isdb.bsky.social#optogenetics is getting attention!! Welcome aboard the Opto-train 🚄🚂
@isdb.bsky.social#optogenetics is getting attention!! Welcome aboard the Opto-train 🚄🚂
@cellsdev.bsky.socialReposted by @isdb.bsky.social❤️ that the #NobelPrize brought the spotlight to #optogenetics. We use the same technique to study how cells move during development, like in this beautiful study by the Solnica-Krezel lab where they show mesoderm can influence endoderm convergent extension in 🐟!
www.sciencedirect.com/science/arti...
@isdb.bsky.socialWoah, such an invaluable resource! You can use this for your lectures too and can make a good resource for students! 🙌
@pbodslab.bsky.socialReposted by @isdb.bsky.socialAn interdisciplinary #embryology book is out as #OER: @ecampusontario.bsky.social ecampusontario.pressbooks.pub/principlesof... A teamwork turned raw lecture recordings into a colloquial writeup. Please pass any feedback & critiques! @isdb.bsky.social @swedbo.bsky.social @socdevbio.bsky.social 🧪🔬
@cellsdev.bsky.socialReposted by @isdb.bsky.socialAre #cilia still hot or ... 👀? Maybe it's time to learn how they are formed! This review by the Pereira lab discusses the structural composition of the distal appendages, how they form the cilia, and how they are regulated in cell cycle and in diseases! www.sciencedirect.com/science/arti...
@cedricboeckx.bsky.socialReposted by @isdb.bsky.socialGreat new study from @knoblich-lab.bsky.social, led by @saku-wong.bsky.social, showing that
human cerebral organoids cultured for over six months can recapitulate postnatal interneuron migration 🧪🧬🧫🧠
www.biorxiv.org/content/10.6...
@haesemeyerlab.bsky.socialReposted by @isdb.bsky.socialCLOK: Truly beautiful new #zebrafish tool for birthdating neurons from the Koyama and Del Bene labs
@epigenometech.bsky.socialReposted by @isdb.bsky.socialEpigenetics News - Old hearts age backwards: transplanted organs adjust to host's biological age www.nature.com/articles/d41...
#Epigenetics #News #Aging #Transplant
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Cancer, immunology, and aging; epigenometech.com
@payalyokota.bsky.socialReposted by @isdb.bsky.socialWhy does the same virus kill one host and spare another? The key is lung imprinting from a previous parasitic infection. Our new study @nature.com offers answers + critical mechanisms! Immense thanks to @KamalmKhanna and our collaborators. 🧵 #Diseasetolerance #NAMs
www.nature.com/articles/s41...:
@natcellbio.nature.comReposted by @isdb.bsky.social☕Vinsland et al. provide a single-cell and spatial transcriptomics atlas of postconceptional week 5–13 human #meninges and perform comparative studies with #meningioma data.
www.nature.com/articles/s41...
@devbiol.bsky.socialReposted by @isdb.bsky.social#DBfeature #LatestResearch 🐠👁️
Regenerated fish retinas are similar to undamaged retinas, but display local patterning errors in comparison with undamaged retinas; new models could test their functionality recovery.
By Deborah L. Stenkamp
@jitumayorlab.bsky.socialReposted by @isdb.bsky.socialOur latest study about how stratified myosin motors at the plasma membrane drive distinct nanoscale clusters that organize into segregated mesoscale active emulsions is out in Science Advances!
Read on to find out more| Science Advances www.science.org/doi/10.1126/...
@ucl-cdb.bsky.socialReposted by @isdb.bsky.social🧬 New research in Nature Cell Biology reveals how tissue flow helps guide immune cell migration and polarity. Congrats to Hoang Anh Le, Jonas Hartmann, Ricard Alert and collaborators! 👏🔬 #CellBiology #Immunology
