@gracefuluniverse.bsky.social#health #agedcare #sustainability #menopause #ecotoxicology #womenshealth #SDGs #aging
Significant association between
elevated blood levels of
toxic metal/metalloid mixtures
(Be, P, V, Cr, Mn, Co, As, Se, Cd, Sb)
and risk of
endometrial cancer
and ovarian cancer
.
dergipark.org.tr/en/pub/jgon/...
@gracefuluniverse.bsky.social#health #agedcare #stroke #menopause #ecotoxicology #publichealth #SDGs #neurology #primaryhealthcare #aging #pathology #gerontology #cardiology
Exposure to multiple metals,
such as antimony(Sb), and lead (Pb)
was consistently associated with
arterial stiffness.
.
link.springer.com/article/10.1...
@toptierquotes.bsky.social“Grow old along with me!
The best is yet to be,”
Robert Browning, Rabbi Ben Ezra (1864), lines 1–2
#TopTierQuotes #RobertBrowning #Poetry #Hope #Faith #Aging #Wisdom #Literature #ClassicPoetry #Optimism #Life #Inspiration #Purpose #Reflection #Encouragement #Poems #Reading #Books #LifelongLearning
@canekforcouncil.bsky.socialIt was great to be back at the Northern Virginia Aging Network's annual legislative breakfast which celebrated 50 years of NVAN's work advocating for our seniors.
#AlexandriaVA #seniors #aging
@aging-us.bsky.social🧬 Longevity & Aging Series (S4, E4):
Dr. Maria Blasco @CNIOStopCancer joins host Dr. Yuan Zhao to discuss “Cross species activity of TERT human telomerase component.”
🎥 https://www.youtube.com/watch?v=DHeysGp9oPg
#Aging #Longevity #Telomeres #Telomerase #Gerontology #OA #MedEd #Interview #Series
@ewingt-phd.bsky.socialBig dogs, little dogs, #aging, #epigenome & #transposons
www.nature.com/articles/d41...
— Study of ~900 dogs from ~120 breeds
— Big dogs die earlier, accumulate epigenetic changes faster
— gene promoters gain methylation
— introns & transposons lose methylation (activate)
via @nature.com
@deborahjross.bsky.socialWe may finally know why big #dogs die younger than smaller ones. Changes in DNA methylation closely tracked biological #aging, in that the dogs with older-than-expected epigenetic ages had a higher risk of death from any cause.
buff.ly/t3VWCAU
@expositionmedals.comSee why 1,290,000 views have watch this vido:
10 Harsh Realities of Being a 77-Year-Old Man youtu.be/dCPOOJzNVFc?... via @YouTube #aging #Babyboomers #retirement
@stanfordneuro.bsky.socialStanford Medicine researchers have identified a key driver of aging: a breakdown in how immune cells clean up after each other and findings point to a possible drug target for extending healthy aging. #BrainHealth #Aging https://med.stanford.edu/news/all-news/2026/07/immune-cells-aging.html
@longevitytech.bsky.socialResearchers say women in Bolotana are reaching 100 at rates that stand out even among the world’s longest-lived people.
Link as first comment.
@jcellsci.bsky.socialIn their Review, Anastasia Zhurikhina, Maia Kirkegaard, Alberto Guarnieri and Hanna Martens discuss the mechanisms and mechanics of #aging.
journals.biologists.com/jcs/article/...
![Schematic showing age-associated disruption of the ECM–cytoskeleton–nucleus mechanotransduction axis. Top, in young cells (i.e. cells from young donors or animals, or early-passage cultures with normal proliferative capacity and morphology), ECM engagement promotes activation and clustering of αβ integrins and assembly of focal adhesions (FAs) containing talin, vinculin, paxillin, FAK and Src. These structures couple the ECM to aligned actin stress fibers and the perinuclear actin cap, enabling force transmission to the nucleus through the LINC complex [SUN1 and/or SUN2 (SUN1/2) with nesprin] and an intact nuclear lamina. PIEZO1-mediated Ca2+ influx promotes FAK–Src and PI3K–AKT signaling and further supports mechanosensitive transcriptional programs mediated by the transcription factors (TFs) YAP/TAZ–TEAD, MRTF–SRF, β-catenin and KLF2 and KLF4 (KLF2/4), impacting genes involved in nuclear envelope (NE) integrity, cytoskeletal integrity, osteogenesis and vasculoprotection, respectively. Bottom, in aged and senescent cells (i.e. cells from aged donors or animals, or replicatively or stress-induced senescent cultures, as defined in the cited studies by stable proliferative arrest together with one or more established senescence markers), integrin composition and focal adhesion assembly are altered, actin organization is disrupted and microtubules (MTs) become excessively stabilized. Reduced SUN2 expression and loss of lamin B1 weaken nucleo-cytoskeletal coupling, de-repress heterochromatin and reduce PIEZO1 expression. Together, these changes blunt mechanosensitive transcriptional responses and impair force transmission from the ECM to the genome. Created in BioRender by Guarnieri, A., 2026. https://BioRender.com/9lv8rls. This figure was sublicensed under CC-BY 4.0 terms.](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:mmkxrjpuoekx6rvbec4bh6nf/bafkreif5ong5qvlytrlvxg3xezswn5ajkpgtbewpe4mmxjifcqv3657p2m@jpeg)
@leibnizfli.bsky.social📢 FLI Colloquium: Prof. Dr. Johannes Hertel
Prof. Dr. Johannes Hertel, University Medicine Greifswald, will speak about "Personalized #models of the #gut #microbiome for #aging #research” on Wednesday, October 28, 3:00 pm at the @leibnizfli.bsky.social.
➡️ More information: bit.ly/3WglnCU
@aging-us.bsky.social#PaperoftheDay: "Small extracellular vesicles as mediators of paracrine senescence in cellular models of aging"
DOI ⬇️
https://doi.org/10.18632/aging.206425
#Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing
@gracefuluniverse.bsky.social#aging #ecotoxicology #oncology
Hexavalent chromium (Cr(VI)) exposure
was consistently associated with
hypermethylation of tumour suppressor genes
(including MLH1 and RAD51),
increased H3K9me2,
and dysregulation of oncogenic microRNAs
including miR-3940-5p
.
academic.oup.com/eep/article/...
@gmj-georgia.bsky.socialBreaking: A landmark study of 255,830 person-years reveals that total testosterone alone is not the strongest predictor of male mortality. Five hormone… #Aging #Clinicaloutcomes #Endocrinology #Hormones #Malehealth #Aging #Clinicaloutcomes #Endocrinology #Hormones #Malehealth https://news.gmj.…
@healthcare-europe.bsky.social🧠 Normal #aging and #Alzheimers disease reshape communication across the #brain in distinct patterns. By differentiating these patterns, researchers from 🇸🇪 @lunduniversity-med.bsky.social are developing a new way for early detection.
@humanumi.bsky.socialBetter cardiovascular fitness was linked to more efficient information processing in older adults — even though fitter participants did not simply respond faster in an attention task.
@14news.comNational Coming Out Day is this weekend. Today, the Aging Untold team talks about coming out later in life. Hear why some members of the LGBTQ+ community may find the courage as seniors at 12:30 p.m. on WFIE.
#NationalComingOutDay #ComingOut #LGBTQIA #Aging #SeniorCitizen #Senior #Seniors
@nile11.bsky.socialThe Emotional Crisis of Aging in America: Why Therapists Say We're Unprepared for the Inner Life of Getting Older
..................
https://nile1.com/the-emotional-crisis-of-aging-in-america-why-therapists-say-were-unprepared-for-the-inner-life-of-getting-older/
..................
#ageism #aging #b
@msipress.bsky.social
