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@genesndiseases.bsky.socialOct 6, 2026, 8:30 AM

#PancreaticDuctalAdenocarcinoma thrives through both #tumor growth and immune suppression.
This study identifies the PKP3–P120 axis as a driver of IL-6/IL-8 signaling, tumor progression and M2 #macrophage polarization.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

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@itmat.bsky.socialSep 24, 2026, 10:37 PM

#TherapeuticPotential of combining #IRE1α and #KRAS inhibition in #PancreaticDuctalAdenocarcinoma doi.org/10.1073/pnas... #PDAC #Hypoxia #Oncology #LiverCancer #SolidTumor #TranslationalScience