Function 🔙 Throw Back Thursday. Pancreatic Ductal Adenocarcinoma, #β-blockers, and #Antihistamines: A Clinical Trial Is Needed. Read:
https://ow.ly/UpJV50ZTYZM #PDAC #pancreas

Function 🔙 Throw Back Thursday. Pancreatic Ductal Adenocarcinoma, #β-blockers, and #Antihistamines: A Clinical Trial Is Needed. Read:
https://ow.ly/UpJV50ZTYZM #PDAC #pancreas
Dr. Jung-Ho Chun at @uwproteindesign.bsky.social is combatting #PDAC remission.
He used an AI-designed IL-21 mimic and induced long-term, durable remissions in mouse models with KRAS inhibitor relapse.
Read the abstract in @cp-cell.bsky.social: https://bit.ly/4dLG27P
📢 Pancreatic Cancer Europe and IQVIA are calling on UK patients with advanced or metastatic PDAC to take part in a research study on treatment outcomes and radioligand therapy.
Learn more: https://survey.cmix.com/F3BA8E5D/7E303C4Q/en-GB
New in @cp-cell.bsky.social! 💡
Human #PDAC showed border-enriched SEPP1+ resident tissue #macrophages near epithelial-mesenchymal transition (EMT)hi tumor cells, suggesting a conserved macrophage-derived selenium niche that supports invasive tumor states.
VesselAlert
Name: EN AVANT 9
MMSI: 244850515
Callsign: PDAC
Type: Tug
Flag: Netherlands
Seen: 02-Oct-2026 04:49:38 CEST
Speed: 7.5 kts
Heading: 232 deg
Dest.: GBSHS
Distance: 62.4 nm
Signal RSSI: 0.0 dBFS
Ship AIS VesselAlert © kx1t - link
VesselAlert
Name: EN AVANT 9
MMSI: 244850515
Callsign: PDAC
Type: Tug
Flag: Netherlands
Seen: 28-Sep-2026 08:50:27 CEST
Status: under way using engine
Speed: 5.1 kts
Heading: 82 deg
Dest.: LANGEOOG
Distance: 67.6 nm
Signal RSSI: 0.0 dBFS
Ship AIS VesselAlert © kx1t - link
#TherapeuticPotential of combining #IRE1α and #KRAS inhibition in #PancreaticDuctalAdenocarcinoma doi.org/10.1073/pnas... #PDAC #Hypoxia #Oncology #LiverCancer #SolidTumor #TranslationalScience
The fourth #neurogastro #highlight from last week's #Vizeralmedizin: Ihsan Ekin Demir was awarded the #research prize for GI #onkology on his work on the interplay between ductal pancreatic carcinoma and the #nervous system.
Congrats, very well deserved! 🏆🎉
In new #pancreascancer research, @muzumdarlab.bsky.social et al. find that the pre-existing molecular state of a #PDAC cell exerts greater influence over how a #KRAS mutation behaves than the identity of the mutation itself.
medicine.yale.edu/cancer/publi...
@molecularomics.bsky.social
Clinical Utility of Circulating Tumor DNA Analysis in Pancreatic Ductal Adenocarcinoma
Clinical Medicine Insights: Oncology
@journals.sagepub.com
Could biomarker selection broaden immunotherapy’s role in pancreatic cancer?
A phase II trial evaluates cemiplimab + gemcitabine in metastatic #PDAC with SWI/SNF alterations. @bottalab.bsky.social @shawnabeynaike.bsky.social
Read the article. https://bit.ly/4xS8V9V
Could #ExtracellularVesicles enable non-invasive #PancreaticCancer detection?
SLC5A3 is elevated in #PDAC-derived vesicles, correlates with poor prognosis, and promotes fibroblast migration and endothelial tubulogenesis.