🧵 8/8: For more details, please check out our preprint:
www.biorxiv.org/content/10.6...

#chromatin #TeamTomo

👋Our September issue's out!
Cover: #embryo implantation mechanics

👉Perspective on #ferroptosis
🔬: #mechanobiology #CellDeath #autophagy #chromatin #RNA #mitosis #circadian control #ribosome #brain #ExtracellularVesicles #transcription #MassSpectrometry & more!

www.nature.com/ncb/volumes/...

We also built NucMetrics, a no-code ImageJ/Fiji tool so the metrics can be easily incorporated into imaging pipelines. Code available in our lab GitHub. #chromatin, #microscopy, #cellbio, #biophysics, #NETosis.

Our expansion of single-cell epigenetics assays continues!

The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform

#Epigenetics #BDrhapsody #CUTandTag #Chromatin #Multiomics #Singlecell #CUTandRUN #ChIPseq #ATACseq

Learn more here: u.epigenome.us/NYjSGQao

Epigenetics Update - A Lactate–H4K12la–HDAC1 epigenetic axis governs microglial state transitions during experimental autoimmune encephalomyelitis in female mice u.epigenome.us/jLW1B75s

#Epigenetics #Chromatin #MultipleSclerosis #H4K12la #HDAC #Microglia
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Gain hi-res insight; epigenometech.com

Join us Friday Sept. 18 @ 12pm CT as Michael Shelley, PhD presents the Monthly Seminar on Physical Genomics: "Modeling Chromatin as an Active Polymer Melt" live on Zoom.

#northwestern #chromatin #genomics #polymer #modeling #biology #biophysics #dna

Registration is free at: tinyurl.com/33daxm9u

Epigenetics Preprint - Cell cycle control of chromatin creates a therapeutic window for epigenetic therapy in tumors u.epigenome.us/tDyhFaBS

Kourosh Hayatigolkhatmi and Saverio Minucci (IRCCS) in biorxivpreprint.bsky.social

#Epigenetics #Preprint #Chromatin
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epigenometech.com

Epigenetics Preprint - X-inactivation escapee domains are CTCF-cohesin independent chromatin compartments u.epigenome.us/d1s1OCC7

agneseloda.bsky.social, mamartirenom.bsky.social, and heard65.bsky.social in biorxivpreprint.bsky.social

#Epigenetics #CTCF #Cohesin #Chromatin
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epigenometech.com

Epigenetics Update - Chromatin context shapes SPT5 regulation of promoter-proximal Pol II, fine-tuning gene expression changes during Drosophila embryogenesis u.epigenome.us/bdTMJPrh

alessandrodulja.bsky.social & Eileen Furlong (embl.org) in Dev Cell

#Epigenetics #Chromatin
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epigenometech.com

Epigenetics Update - Epi-Allele elicits compensatory expression of the non-targeted allele and prevents haploinsufficiency in dominant genetic diseases u.epigenome.us/xphNOEGk

#Epigenetics #EpiAllele #Chromatin #Haploinsufficiency #iPSCs
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Gain deeper insights; epigenometech.com

Epigenetics Update - Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state u.epigenome.us/0LPYh8xZ

Amoldeep Kainth & Alexander Ruthenburg (University of Chicago) in Mol Cell

#Epigenetics #Chromatin #WDR5 #KMT2A #MLL
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epigenometech.com