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Version devBuilt at: 2026-10-10 01:38:52 EDT

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@prepub-singlecell.bsky.socialOct 10, 2026, 1:00 PM

HIV remodels germinal centers through T follicular helper cell loss #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757815v1

@prepub-singlecell.bsky.socialOct 10, 2026, 1:00 PM

Point-Process Modelling of Cell-Type Interaction Structure in CosMx Glioma Data for Hypothesis-Driven Tumor Inference from scRNA-seq #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.02.756019v1

@prepub-singlecell.bsky.socialOct 10, 2026, 7:00 AM

DEPICT enables sample-centric therapeutic prioritization across evolving and spatially heterogeneous tumor states #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.756157v1

@prepub-singlecell.bsky.socialOct 9, 2026, 7:01 PM

DECONVersation: Single Cell Foundation Model-Derived Embeddings for Robust Cell Type Deconvolution of Bulk RNA-seq #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.02.756356v1

@prepub-singlecell.bsky.socialOct 9, 2026, 7:00 PM

NECTIN4 defines a subtype-dependent tumor state coupling enfortumab vedotin targetability to antitumor immunity in bladder cancer #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757381v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:02 PM

STEER-seq: a recombinase based platform for pooled multimodal single-cell perturbation screening #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757551v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:02 PM

High-throughput identification of chromatin-opening transcription factors #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757445v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:02 PM

Uni-TINT: Unifying T and Innate Lymphoid Cell Taxonomy with a high resolution, pan-disease and pan-tissue single-cell transcriptomic atlas #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10811197/latest

@prepub-singlecell.bsky.socialOct 9, 2026, 4:01 PM

Repeated malaria exposure reprograms Vδ2+ γδT cell chromatin accessibility and immune function toward a reversible hyporesponsive state #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.02.755737v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:01 PM

Random mtDNA mutagenesis maps genotype-phenotype associations across metabolic contexts and lineages #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757705v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

scPRIME-seq uncovers synchronized multimodal molecular collapse facilitated by pre-neoplastic epigenetic burden in prostate cancer #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757464v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

Ligand-specific endothelial Notch signaling coordinates brain pericyte specification and expansion #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.05.756680v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

The dark transcriptome mouse organogenesis cell atlas #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.06.756869v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

GRASS-MIL: graph-based representation and discovery of phenotype-associated spatial structures with multiple instance learning #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757722v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

Paired single-nucleus and spatial transcriptomics of the lung adenocarcinoma invasion sequence reveal niche domains and candidate reversal compounds #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757757v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

Neutrophils orchestrate pre-metastatic immunosuppressive bone marrow remodeling during prostate cancer metastasis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757800v1

@prepub-singlecell.bsky.socialOct 9, 2026, 4:00 PM

A High-Content Pseudotime Framework for Morphological Profiling of Dengue Virus Inhibitors from a Drug-Repurposing Library #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.06.757061v1

@braithwaiteat.bsky.socialOct 9, 2026, 2:55 PM

​Which in vitro model best reflects human disease? We compared scRNA-seq profiles of >150K PBMCs across 11 stimuli, mapping them against inflammatory diseases like SLE to highlight the most clinically relevant models. Free data: doi.org/10.1186/s130... 🧪🧬🖥️ #immunosky #scRNAseq #SingleCell

A multi-panel figure summarizing the experimental workflow and single-cell RNA sequencing results for in vitro stimulated immune cells.
  
The top left panel illustrates the experimental workflow, showing healthy donor PBMCs treated with immunomodulators for 48 hours, followed by cell fixation, SPLiT-Seq single-cell barcoding, RNA sequencing, and downstream comparative analysis.  

The bottom left panel displays a UMAP plot showing the distinct clustering of various immune cell types across myeloid and lymphoid lineages, including monocytes, B cells, T cells, and NK cells.  

The right panel features a grid plot comparing the responses of these specific immune cell types across 11 different stimulations. This plot highlights the mean fold change (represented by color) and the number of differentially expressed genes (represented by the size of the squares) per cell type and stimulation condition.
@phytolearning.bsky.socialOct 9, 2026, 2:46 PM

¿Qué es la tecnología Single Cell? 🧬 El Dr. José Miguel Álvarez, director de PhytoLearning, te explica esta herramienta clave para entender cómo actúan los genes en una sola célula y su impacto en múltiples enfermedades.

#workshop #singlecell #phyto #ciencia #mesdelaciencia

@prepub-singlecell.bsky.socialOct 9, 2026, 1:01 PM

A cellular atlas of Astyanax mexicanus embryogenesis reveals principles of developmental microevolution #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757402v1

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