⏩ Possible projects are: variational #freeenergy methods, thermodynamics of #solvationshells, #constant-pH simulation methods, Markovian #thermodynamics, as well as functional mechanisms of the #ribosome, fatty acid synthase, #CRISPR/Cas, or intrinsically disordered proteins #IDP

(2/2) Arg and Lys promote condensation more readily than simpler cationic amino acids, highlighting how amino acid chemistry may have shaped early RNA–peptide organization.
#OriginOfLife #RNA #Ribosome
doi.org/10.64898/202...

🚨 Last chance for early-bird registration for #SRCKC26!

Join researchers from across the field to explore emerging concepts in #ribosome heterogeneity, specialized translation, quality control and more.

Today is also the deadline to submit an abstract for consideration.

🔗 bit.ly/43Vb9so

Mycotoxin associated with hibernating ribosomes in human cells 🔽 #Ribosome

How can a single antibiotic halt translation across all domains of life? 🧬

Our new study in Nucleic Acids Research reveals how Sparsomycin traps active ribosomes through a conserved mechanism.
academic.oup.com/nar/article/...

#Ribosome #Translation #StructuralBiology #Antibiotics #RNA #iTPseq

Nucleolar dynamics are determined by the ordered assembly of the #ribosome. New study from Jessica Sheu-Gruttadauria and collegues (UCSF):
rupress.org/jcb/article/...

#Biophysics #RNAbiology #Nucleolus

PAPER ALERT!!!
For over 20 years, circular pre-rRNA intermediates were thought to be a specific and universal requirement for archaeal ribosome biogenesis.

doi.org/10.1261/rna....

#Archaea #Ribosome #RNAProcessing
#Archaeasky #RNAsky

New preprint! 👀RNAse activity has to be tightly regulated.✂️🧬Here, we present the dynamic architecture of the conserved Rixosome complex – a major player in ribosome maturation and heterochromatin maintenance. Our results give insights into its mode of activation.👇

#cryoEM #Ribosome #RNA

👋Our September issue's out!
Cover: #embryo implantation mechanics

👉Perspective on #ferroptosis
🔬: #mechanobiology #CellDeath #autophagy #chromatin #RNA #mitosis #circadian control #ribosome #brain #ExtracellularVesicles #transcription #MassSpectrometry & more!

www.nature.com/ncb/volumes/...

#RNASky #ribosome Manipulation of protein translation and stem cell self-renewal by CRISPR activation of rRNA transcription | Science www.science.org/doi/10.1126/...

📰Happy to share our preprint.🥳Here we investigate🔬, the essential role of the conserved RNA helicase Drs1. We show that its engagement and activity license timely incorporation of 25S rRNA domain III into maturing nucleolar pre-60S subunits.👇
doi.org/10.64898/2026.09.05.749353
#cryoEM #ribosome #RNA