Inotodiol activates LXRβ and promotes PPARδ-dependent #SIRT3 transcription, engaging the LXRβ/SIRT3/PGC-1α pathway to restore mitochondrial function and counter age-associated #MuscleWasting and #MetabolicDysfunction.
@sigtrans-sttt.bsky.social
@sigtrans-sttt.bsky.socialInotodiol activates LXRβ and promotes PPARδ-dependent #SIRT3 transcription, engaging the LXRβ/SIRT3/PGC-1α pathway to restore mitochondrial function and counter age-associated #MuscleWasting and #MetabolicDysfunction.
@mitoworld.bsky.social#Mitochondria are central to #SkeletalMuscle Health, including #metabolism #bioenergetics #proteostasis #genomics & #regeneration, according to Dr. Sandri & Dr. Vainshtein in @natureportfolio.nature.com:
#cachexia #musclewasting #mitometabolism #mitoscientists #UMDF