@mitoworld.bsky.social#Mitochondrialdiseases are central in the #rarediseases research realm, but recently are getting more recognition for the #metabolicdysfunction associated. @natmetabolism.nature.com looks at the metabolism angle in this latest viewpoint:
@itmat.bsky.socialEstablishing #Fruitfly model to discern #MolecularMechanisms of #Sleep & #CircadianClock related #MetabolicDysfunction for developing #TherapeuticOpportunities elifesciences.org/articles/108... @weljielab #Metabolomics #TranslationalScience
@sigtrans-sttt.bsky.socialInotodiol activates LXRβ and promotes PPARδ-dependent #SIRT3 transcription, engaging the LXRβ/SIRT3/PGC-1α pathway to restore mitochondrial function and counter age-associated #MuscleWasting and #MetabolicDysfunction.
@andrewtosolini.bsky.socialReally pleased for David and Chloe to see this published. Was a great collaboration
#ALS #MND #SOD1 #metabolicdysfunction
@uclqsion.bsky.social