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@plosbiology.orgOct 10, 2026, 12:05 PM

What are the #epigenetic mechanisms regulating cellular proteostasis? This study shows that a subunit of the COMPASS histone methyltransferase complex controls ultradian proteostasis gene expression through methylation at #proteostasis gene promoters.
🧪 #AcademicSky
plos.io/4emgONz

This research article is titled "The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics," by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michael J Jurczak, Silvia Liu, Bokai Zhu
@sigtrans-sttt.bsky.socialOct 10, 2026, 12:01 PM

#Mitochondrial dysfunction contributes significantly to human disease pathogenesis.

This review connects #proteostasis, biogenesis, mitochondrial dynamics, and mitophagy with disease mechanisms and emerging therapeutic strategies. @ub.edu

#STTT #OpenAccess: doi.org/10.1038/s413...

Mitochondrial quality control in health and disease: mechanisms and therapeutic targets
@plosbiology.orgOct 9, 2026, 8:05 AM

What are the #epigenetic mechanisms regulating cellular proteostasis? This study shows that a subunit of the COMPASS histone methyltransferase complex controls ultradian proteostasis gene expression through methylation at #proteostasis gene promoters.
🧪 #AcademicSky
plos.io/4emgONz

This research article is titled "The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics," by Syeda Kubra, Michelle Sun, William Dion, Yu Bian, Ahmet Catak, Hannah Luong, Haokun Wang, Yinghong Pan, Jia-Jun Liu, Aishwarya Ponna, Lijun Liu, Ian Sipula, Jian-Hua Luo, Michael J Jurczak, Silvia Liu, Bokai Zhu
@royalsocietypublishing.orgOct 4, 2026, 9:00 AM

A new theme issue focuses on our recent understanding of the #proteostasis network, from molecular cell biology to systems biology. Papers explore how the network is modulated by differences in cell types and age and how it is reshaped by stress and disease. Read: buff.ly/BaghEM4

@ericchevet.bsky.socialOct 4, 2026, 6:12 AM

Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: A redox switch on CDC48 regulates peroxisomal function via controlling peroxisome-associated protein degradation www.nature.com/articles/s41...

@royalsocietypublishing.orgOct 2, 2026, 7:15 PM

A new theme issue focuses on our recent understanding of the #proteostasis network, from molecular cell biology to systems biology. Papers explore how the network is modulated by differences in cell types and age and how it is reshaped by stress and disease. Read: buff.ly/BaghEM4

@sigtrans-sttt.bsky.socialOct 1, 2026, 7:37 AM

This study uncovers how polymeric #Alpha1Antitrypsin accumulation perturbs Paneth cell #Proteostasis via #ERstress and impaired lysosomal clearance, linking deficiency to severe intestinal inflammation.

#STTT #OpenAccess: doi.org/10.1038/s413...

Polymeric alpha-1 antitrypsin perturbs Paneth cell proteostasis and exacerbates intestinal inflammation
@ibmp-cnrs.bsky.socialSep 30, 2026, 6:49 AM

The global Plant Proteostasis community is gathering in Strasbourg for the 5th International Conference on Plant Proteostasis 2026 (Oct 14-16) at @ibmp-cnrs.bsky.social ! 🌍🌱
🔗 proteostasis-26.sciencesconf.org
#PlantScience #Proteostasis

@pcavanderwel.bsky.socialSep 28, 2026, 1:47 PM

Webinar: "Proteostasis Consortium Seminar:
Amyloid Polymorphism: More than just the Fibril Core”. by Sheena Radford @radford-lab.bsky.social

(presumably about the cruciial ‘fuzzy coat’ of #amyloid fibrils )

Sep 30, 2026; #Proteostasis consortium seminar

www.proteostasisconsortium.com/seminars/

@ericchevet.bsky.socialSep 27, 2026, 4:41 AM

Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Protein entanglement misfolding in proteasomal degradation or near-native misfolded states persistence www.nature.com/articles/s41...

@akohler-mito.bsky.socialSep 23, 2026, 11:15 AM

📢 We're recruiting!

A 2-year postdoctoral fellowship is available in our lab at Umeå University!

Please share with interested colleagues!

🔗 umustipendie.varbi.com/en/what:job/...
📅 Application deadline: 31 October 2026

#Postdoc #Mitochondria #Proteostasis #AcademicJobs #LifeScience

@akohler-mitolab.bsky.socialSep 23, 2026, 11:15 AM

📢 We're recruiting!

A 2-year postdoctoral fellowship is available in our lab at Umeå University!

Please share with interested colleagues!

🔗 umustipendie.varbi.com/en/what:job/...
📅 Application deadline: 31 October 2026

#Postdoc #Mitochondria #Proteostasis #AcademicJobs #LifeScience

@freddietheodoulou.bsky.socialSep 20, 2026, 7:56 AM

Looking forward to hearing the latest plant #proteostasis research next month in Strasbourg! 🌱 plantscience

@ericchevet.bsky.socialSep 20, 2026, 5:05 AM

Good morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Encoded and non-genetic protein variants expand human functional proteome www.nature.com/articles/s41...

@sigtrans-sttt.bsky.socialSep 20, 2026, 1:50 AM

This study identifies SCFJFK as an E3 ligase that mediates #RUNX2 degradation, and a reciprocal RUNX2–JFK feedback loop linking #Proteostasis to #Osteogenesis and the pathogenesis of #CleidocranialDysplasia. @pku1898.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

SCFJFK regulates osteoblast differentiation through targeting RUNX2
@suaybuestuen.bsky.socialSep 19, 2026, 1:16 PM

Can’t wait for the Plant Proteostasis Conference! 🌱 🔥The program looks 👍 & our entire Lab will be there! Especially excited to see @margotraffeiner.bsky.social & @shanshuo.bsky.social present our work on proteotoxic stress, cell-type-specific autophagy & more. Best community ever 💚 #proteostasis

@jcellsci.bsky.socialSep 17, 2026, 4:37 PM

We're now accepting submissions for our next special issue, which will focus on 'Proteostasis' and will be coordinated by two of our Academic Editors, Pedro Carvalho and Tamotsu Yoshimori.
Submission deadline: 2 November
Find out more: journals.biologists.com/jcs/pages/pr...

#proteostasis

@mitoworld.bsky.socialSep 16, 2026, 2:58 PM

This week's highlights from @cvasilescu.bsky.social @biomednews.bsky.social include:

💥 #Mitochondria in #Neurobiology: Cellular Vulnerability to Therapeutic Opportunity
💥ND6 Restores #Vision in #MitochondrialDisease
💥Mitochondrial #Proteostasis Links #Diabetes & #Sarcopenia

#UMDF #mitoscientists

@mitoworld.bsky.socialSep 16, 2026, 2:37 PM

#Mitochondria are central to #SkeletalMuscle Health, including #metabolism #bioenergetics #proteostasis #genomics & #regeneration, according to Dr. Sandri & Dr. Vainshtein in @natureportfolio.nature.com:

mitoworld.org/hallmarks-of...

#cachexia #musclewasting #mitometabolism #mitoscientists #UMDF

@jhumimmunity.orgSep 15, 2026, 1:45 PM

ER #proteostasis failure in HYOU1 deficiency alters #Bcells, #neutrophils, and #interferon signaling. New study from Aida Idani, Raphael Carapito, Seiamak Bahram @seiamak.bsky.social @unistra.fr and colleagues:
rupress.org/jhi/article/...

#InbornErrorsOfImmunity

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