#HSP90 promotes ROC1 stability in #LungAdenocarcinoma by shielding it from CHIP-mediated #Ubiquitination and degradation. HSP90 inhibition restores ROC1 destabilization and suppresses #tumor growth, defining an HSP90–CHIP–ROC1 axis.

#STTT #OpenAccess: doi.org/10.1038/s413...
#ClinicalTrials

📰Research article:

🐟The shared immunometabolic responses between dexamethasone-induced hepatobiliary syndrome and GCRV II-caused hemorrhagic disease reveal the pivotal role of autophagy and #Hsp90 activity in metabolic and infectious diseases

📝 doi.org/10.1016/j.watbs.2025.100400

#Aquaculture