@sigtrans-sttt.bsky.social#HSP90 promotes ROC1 stability in #LungAdenocarcinoma by shielding it from CHIP-mediated #Ubiquitination and degradation. HSP90 inhibition restores ROC1 destabilization and suppresses #tumor growth, defining an HSP90–CHIP–ROC1 axis.
@fudiwang.bsky.socialThrilled our paper is published in @cellpress.bsky.social
MARCH7, an E3 ubiquitin ligase, acts as a ferro‑guardian against ferroptosis. Open for collaborations😘 Full text: doi.org/10.1016/j.ce...
#ferroptosis #ironmetabolism #ubiquitination
@abbsjournal.bsky.social✨USP11-mediated deubiquitination regulates the protein stability of NR2F1
www.sciengine.com/ABBS/doi/10....
#USP11
#deubiquitinase
#NR2F1
#tumor_dormancy
#ubiquitination
@abbsjournal.bsky.social🎊USP11-mediated deubiquitination regulates the protein stability of NR2F1
www.sciengine.com/ABBS/doi/10....