Antimalarial drugs may persist inside #mosquitoes for up to 5 days after a blood meal, according to a new @yaleschoolofmed.bsky.social study. Could this prolonged exposure affect #malaria parasite development, transmission, or #drugresistance? lnkd.in/p/exdVQGta

📍Check this published paper in #PathogensMDPI 2023!

🔬A Novel Inhibitor against the Biofilms of Non-Tuberculous Mycobacteria by Parvinder Kaur et al.

🔗Read more here: https://www.mdpi.com/2076-0817/13/1/40

#DrugResistance #NTM #Mycobacteria

Injectable #nanodevices could provide effective treatment for drug-resistant #glioblastoma

cc @nanoappsmedical.bsky.social @cellrep7.bsky.social @amandascott2023.bsky.social
#NanoApps #Research #SDGs #GHCE #Nanodevice #drugresistance #NanoInjection www.nanoappsmedical.com/injectable-n...

🧬What drives tumor #drugresistance?
This Review explores the multidimensional roles of #extracellularvesicles in drug resistance, covering resistance mechanisms, biomarkers, engineered EV-based drug delivery, and clinical translation.
www.oaepublish.com/articles/evc...
@princess-vimentin.bsky.social

Why does #ColorectalCancer keep resisting #5Fluorouracil chemotherapy?
This study shows that arachidonic acid–driven lipophagy sustains resistant cells, suggesting a strategy to restore chemotherapy sensitivity. #DrugResistance
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...

#WEHI researchers developed #Partita, a high-density mouse genome-wide #CRISPRa library (263,460 sgRNAs), mapping #cancer dependencies, Irx5-driven venetoclax resistance, and in vivo MYC-synergistic oncogenes (Runx2/Runx3/Csf1r). 🐭🤖 #ScienceAdvances2026 #DrugResistance #InVivoScreening

We show that combination therapies that stimulate antitumour immunity promote the immune-mediated elimination of KRAS-G12C inhibitor-resistant subpopulations, providing a potential strategy to overcome drug resistance that may have relevance in broader therapeutic settings. #KRAS #DrugResistance

A question on #Antimicrobials #DrugResistance tabled by Baroness Bennett of Manor Castle on 01-09-2026 has been answered by Baroness Hayman of Ullock. https://questions-statements.parliament.uk/written-questions/detail/2026-09-01/HL2794

GLP-1 drugs show resistance in some patients, study reveals

🤖 IA: It's not clickbait ✅
👥 Users: It's not clickbait ✅

#medicalresearch #geneticvariants #drugresistance

👇👇👇

🤔 Do lysosomal ABC transporters drive drug resistance? This study says unlikely—halving target drug concentration would need huge gradients, likely toxic to lysosomes.

📄 www.mdpi.com/1999-4923/17...

#DrugResistance #ABCTransporters #Cancer

#DrugResistance limits #Androgen-targeted therapy in castration-resistant #ProstateCancer.

A self-assembling nano-#PROTAC degrades AR, AR-V7, and HSP90, suppressing enzalutamide-resistant tumor growth and extending survival in mice.

#STTT #OpenAccess: doi.org/10.1038/s413...