The phase 3 ANCHOR trial finds that anlotinib + CapeOX shows similar antitumor activity to bevacizumab + CapeOX in RAS/BRAF wild-type #Metastatic #ColorectalCancer, but does not meet the prespecified noninferiority margin for PFS.

The phase 3 ANCHOR trial finds that anlotinib + CapeOX shows similar antitumor activity to bevacizumab + CapeOX in RAS/BRAF wild-type #Metastatic #ColorectalCancer, but does not meet the prespecified noninferiority margin for PFS.
Single-cell transcriptomic and H3K27ac epigenomic profiling identify inflammation-enriched LRRK2⁺ B cells and their epigenetic remodeling, providing new insights into inflammation-to-cancer transition in colorectal tumorigenesis.
doi.org/10.59717/j.x...
#SingleCellSequencing #colorectalcancer
Only half of eligible 54-year-olds in England completed free bowel cancer screening test kits, according to NHS data. Health officials warn that low uptake rates delay … #Bowelcancer #Colorectalcancer #Earlydetection #NHS #Publichealth #Bowelcancer #Colorectalcancer #Earlydetection #NHS #Public…
A prospective observational study of treatment sequencing with regorafenib and FTD/TPI in metastatic #ColorectalCancer: The OSERO study. www.nature.com/articles/s41...
🧬 This study finds the ZMYM2-ANXA9 pathway is a key driver of chemotherapy resistance in colorectal cancer. The FLT3 inhibitor G749 suppressed ANXA9, restored chemotherapy sensitivity, and reduced tumor burden in preclinical models. 🎯 #ColorectalCancer
www.mdpi.com/2227-9059/13...
🩺 Not standard treatment: Aspirin is not routine for cancer, bleeding risk high.
🦠 Most evidence: Colorectal cancer, but mixed results and risks.
⚠️ Main risk: GI bleeding, serious side effects.
#AspirinCancer #ColorectalCancer #CancerRisks
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The anti-TFRC antibody PPMX-T003 suppresses #ColorectalCancer growth and metastatic colonization in preclinical models, highlighting iron-dependent tumor survival as a target for limiting metastatic progression.
#STTT #OpenAccess: doi.org/10.1038/s413...
#AntibodyTherapy #TargetedTherapy
A new study in @lancetgastrohep.bsky.social found that #aspirin did not reduce recurrence or death after curative-intent treatment of colorectal liver metastases. Notably, previous studies suggested benefits in other #ColorectalCancer settings. #CancerResearch 🧪
#GIT
Validated logistic model predicts anxiety (80.1% incidence) in first-degree relatives of colorectal cancer patients via education, age, comorbidity, and risk perception.
Details: https://www.maxapress.com/article/doi/10.48130/git-0026-0012
#ColorectalCancer #Anxiety #PredictiveModel
@eurekalert.bsky.social
www.eurekalert.org/news-release...
Obesity and High Fat Risk: The findings explain on a molecular level why obesity & high fat diets are significant clinical risk factors for advanced #colorectalcancer progression & #metastasis
#Medsky🧪 #oncosky #publichealth The study identifies a direct cellular mechanism linking dietary fat, lipid metabolism, and the spread of #colorectalcancer (CRC) to other organs, primarily the liver .
📢 Featured Special Issue of Onco Therapeutics! "Phytochemicals for Colorectal Cancer Therapy" reviews natural compounds, curcumin, MMPs & tumor microenvironment in CRC.
📢 Featured Special Issue of Onco Therapeutics! "Phytochemicals for Colorectal Cancer Therapy" reviews natural compounds, curcumin, MMPs & tumor microenvironment in CRC.
🆕New in #JExBio🆕 Extracellular Vesicles Drive Invasive Characteristics and Matrix Remodelling in Organotypic Models of Colorectal Cancer Progression #extracellularvesicles #colorectalcancer #extracellularmatrix #metastasis isevjournals.onlinelibrary.wiley.com/doi/epdf/10....
This is the first in our Meet the Team series. We’ll be introducing more of the people behind Microb-AI-ome soon! 🔬
#MeetTheTeam #MicrobAIome #Microbiome #ColorectalCancer #AIinHealth
@cosybio-uhh.bsky.social
4/4
Colorectal cancer rates are rising fast in younger adults across the Eastern Mediterranean 🌍🔎. New study highlights dramatic country-by-country differences - and a 59% projected increase by 2050. What’s driving this surge?
www.news-medical.net/news/2026092... #ColorectalCancer #GlobalHealth
#ColorectalCancer in many cases has genomic underpinnings that the #OncNurse should be aware of, according to a presentation at #ONSBridge2026 by Kathleen Calzone, PhD, RN, AGN-BC, FAAN, a research geneticist at the The NCI.
Read about her research here: https://bit.ly/4AwVJti
How Walking Boosts Colorectal Cancer Recovery #cancer #CancerRecovery #ColonCancer #ColorectalCancer #ConsistantWalking #CosistantExercise #exercise #walking https://megadoctornews.com/how-walking-boosts-colorectal-cancer-recovery/