In #SensorineuralHearingLoss, pure-tone average phenotyping identified more genome-wide significant loci and higher heritability than diagnostic code–based phenotyping.

ja.ma/3TzNFHQ

Among patients receiving radiotherapy for #HeadAndNeckCancer, higher skeletal muscle and lower intermuscular adiposity on pretreatment #ComputedTomography were associated with improved overall survival.

ja.ma/4rUgVFM

In #SensorineuralHearingLoss, pure-tone average phenotyping identified more genome-wide significant loci and higher heritability than diagnostic code–based phenotyping.

ja.ma/4yMY0zl

Among patients receiving radiotherapy for #HeadAndNeckCancer, higher skeletal muscle and lower intermuscular adiposity on pretreatment #ComputedTomography were associated with improved overall survival.

ja.ma/4hAMGQQ

Persistent unilateral #Sinonasal obstruction with a maxillary sinus mass and palatal erosion may indicate sinonasal ameloblastoma, a rare locally infiltrative odontogenic epithelial tumor. ja.ma/4AIvPTo

A tracheostomy-specific #Tracheostomy risk-tier system for children separated prolonged hospitalization and in-hospital mortality better than All Patient Refined Diagnosis Related Group severity classification. ja.ma/4rpdJle

For patients with #ObstructiveSleepApnea treated with hypoglossal nerve stimulation, low arousal threshold was associated with a shift from 3-month adherence to 6-month nonadherence. ja.ma/4roCjTf

A 34-year-old man with no significant medical history presented with progressive dysphonia, dysphagia, and an infiltrative laryngeal mass that remained nondiagnostic on multiple biopsies. What was the diagnosis? ja.ma/4dNuEbt

Interview with Dana S. Guggenheim, BA, and Justin S. Golub, MD, MS, authors of Newborn Hearing Screening in the Otoferlin Gene Therapy Era. Hosted by Paul C. Bryson, MD, MBA. ja.ma/4rcqAap

Among patients undergoing head and neck #FreeFlap reconstruction or #TransoralRoboticSurgery, adjunctive #Suzetrigine was associated with lower inpatient opioid use and similar postoperative pain scores. ja.ma/4Akh0Gs

💬 Editorial: A single narrative arc and the And–But–Therefore framework can help scientific findings clearly communicate the problem, the evidence gap, and the reason the audience should care.

ja.ma/472YwwR

For #HeadAndNeckSquamousCellCarcinoma surveillance, tissue-informed #ctDNA positivity was sometimes the first sign of recurrence and showed high positive and negative predictive value.

ja.ma/4igsx38

📣 Special Communication: In #PrimaryHyperparathyroidism, imaging should be reserved for after biochemical diagnosis, and #Ultrasonography is the preferred first study because it involves no ionizing radiation.

ja.ma/4yt6ACZ

In #PapillaryThyroidCarcinoma, #TERT promoter variants increased with age across 3 cohorts, indicating that molecular status may explain much of the worse prognosis associated with older age.

ja.ma/4x7bunN