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@genesndiseases.bsky.socialSep 17, 2026, 4:20 PM

Decoding thyroid cancer progression requires understanding #m6A‑regulated drivers.
IGF2BP2 is upregulated in #PapillaryThyroidCarcinoma, promoting malignancy via SPRY1 and MAPK/MEK/ERK signaling, enhanced by TGF‑β/SMAD4.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

@jamaotolaryngology.comSep 6, 2026, 2:29 PM

In #PapillaryThyroidCarcinoma, #TERT promoter variants increased with age across 3 cohorts, indicating that molecular status may explain much of the worse prognosis associated with older age.

ja.ma/4x7bunN

Three bar charts display TERT variations (%) by age group across MDACC/VUMC/UW, TCGA, and GENIE studies. All charts show an increasing trend of TERT variations with age, particularly from 45-55 years onward, peaking in the ≥65 age group. Associated data tables provide TERT status counts.
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