@biorxivpreprint.bsky.social Tissue retention of dendritic cells drives age-associated protective tolerogenic lymphoid structures
www.biorxiv.org/content/10.6...

@biorxivpreprint.bsky.social CD19 CAR Engineered T Regulatory Cells Promote Durable Immune Tolerance in Experimental Systemic Lupus Erythematosus
www.biorxiv.org/content/10.6...

@biorxivpreprint.bsky.social The transition to postpartum lactation establishes a state of maternal antiviral resilience
www.biorxiv.org/content/10.6... @kelliejurado.bsky.social @pennmedicine.bsky.social

@biorxivpreprint.bsky.social Microplastics disrupt a cDC1-CD8/NKT regulatory circuit that restrains plasma cell accumulation after injury
www.biorxiv.org/content/10.1... @ksadtler.bsky.social

@biorxivpreprint.bsky.social Restoration of deficient IL-15 signaling enhances innate lymphoid cell immunity in brain metastasis
www.biorxiv.org/content/10.6... @dlawsonlab.bsky.social @ucirvine.bsky.social

Reviving low-affinity glycan-targeting CAR with combinatorial design @cp-cellrepmed.bsky.social
www.cell.com/cell-reports...

Lipid-engineered antibody-based therapeutics target inflamed joints and lymph nodes to enhance rheumatoid arthritis treatment @cp-cellrepmed.bsky.social
www.cell.com/cell-reports...

MAIT cells show promise as an immunotherapy tool with both adaptive and innate characteristics
www.cell.com/med/abstract...

Lymph node lymphangiogenesis encapsulates activating germinal centers to constrain their size, which enhances clonal selection and protective antibody responses @cp-immunity.bsky.social
www.cell.com/immunity/ful... @carlanowosad.bsky.social @thelundlab.bsky.social

CD8+ Tem GZMK+ to GZMB+ ratio distinguishes healthy from disease-associated trajectories and predicts mortality risk @cp-immunity.bsky.social
www.cell.com/immunity/ful... @washumedicine.bsky.social @nationwidekids.bsky.social @kingscollegelondon.bsky.social

Microglia drive alcohol-induced sedation, motor impairment, and synaptic and neuronal loss through MyD88-dependent perisynaptic extracellular matrix disruption @cp-immunity.bsky.social @davalos.bsky.social @clevelandclinic.bsky.social @evipaouri.bsky.social
www.cell.com/immunity/ful...

NK cells contribute to early inflammatory responses induced by mRNA vaccination, yet their depletion does not impair the magnitude of long-term adaptive immune
doi.org/10.1093/jimm...
@jimmunol.bsky.social

Influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates
www.science.org/doi/10.1126/...

Extracellular matrix–targeted TNC-scFv armoring enhances CAR T cell persistence and antitumor activity in solid tumors
doi.org/10.1126/scia...

Adjuvant-induced prophylaxis with CpG oligodeoxynucleotide-schizophyllan complex is a promising approach to enhancing host resistance against respiratory virus infection
doi.org/10.1126/scia...

Canonical Wnt induction by OTULIN prevents keratinocyte death and skin inflammation
www.science.org/doi/10.1126/...

Spatiotemporal co-regulation of IL2 and TCR receptors reveals early antigen-driven synaptic synergy in human CD8+ T cells @natcomms.nature.com @ox.ac.uk
www.nature.com/articles/s41...

Anti‑CD28 CAR T cells largely sparing CD8 T & NK cells while preferentially depleting CD4 T cells in T lineage malignancies, particularly TH2 + TH17
www.nature.com/articles/s41... @natcomms.nature.com @lmu.de

Review @sigtrans-sttt.bsky.social
Bioengineering strategies for improving the immunogenicity of mRNA vaccines
www.nature.com/articles/s41...

Immune genetic associations of antibody Fc-profiles across twins @natcomms.nature.com @ragoninstitute.bsky.social #Alter #Lauffenburger
www.nature.com/articles/s41...