Proteomic and metabolomic profiling depicts the functional landscape of the Medicago truncatula symbiosome

B cell-guided inflammatory cascade perpetuates ICI-mediated colitis

Selective control of HLA-DRB1 and HLA-DQA1 transcription through DR/DQ super enhancer microelements

A secreted protein from Hungatella hathewayi inhibits colorectal cancer by reprogramming intratumoral CD14b+ macrophages

Mitochondrial Raf1 regulates glutamine catabolism

Integrated stress response inhibition decouples cardiotoxicity from anthracycline chemotherapy while enhancing antitumor efficacy

Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation

Blautia wexlerae ameliorates ulcerative colitis via metabolic remodeling of the gut microbiota

Sharing is not caring: Near-germline and polyreactive memory B cells in primary dengue

Parkinson’s gut dysmotility: A role for DMV cholinergic neurons

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Understanding carriage of Streptococcus pyogenes directly from the human host

From heart to BAT: Rethinking mouse models of human BAT

FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma

Disrupted glucocorticoid rhythms selectively induce severe skeletal muscle insulin resistance and uncouple obesity from hepatic steatosis

Butyrophilin 3A1 engages the CDR2δ loop of the Vγ9Vδ2+ T cell receptor

Structure-based design of soluble prefusion-stabilized herpes simplex virus type 2 glycoprotein B antigens

Staphylococcus aureus biofilm infection impairs efferocytosis in wound-macrophages via induction of a MARCOhiMERTKlo subset

Atomistic TCR-pMHC interactions bias CD8 memory fate within a single antigen-specific repertoire

Berberine, a natural molecular glue degrader, overcomes CML resistance via TRIM28-mediated HIF1α ubiquitination and subsequent ferroptosis