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@jamaneurology.com Sep 6, 2026, 2:33 PM

Among patients with #BranchAtheromatousDisease-related #IschemicStroke, intravenous #Tirofiban plus aspirin did not reduce early neurological deterioration or new stroke compared with aspirin alone.

JAMA Neurology RCT on Tirofiban+aspirin vs. placebo+aspirin for stroke. 970 patients (607M, 363F, median 63y) in China. Findings: No significant difference in early neurological deterioration or new stroke incidence between groups. Graph shows similar cumulative incidence for both (HR 0.88, P=.39).

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