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@jamaneurology.comSep 6, 2026, 2:33 PM

Among patients with #BranchAtheromatousDisease-related #IschemicStroke, intravenous #Tirofiban plus aspirin did not reduce early neurological deterioration or new stroke compared with aspirin alone.

ja.ma/4cYrWQ8

JAMA Neurology RCT on Tirofiban+aspirin vs. placebo+aspirin for stroke. 970 patients (607M, 363F, median 63y) in China. Findings: No significant difference in early neurological deterioration or new stroke incidence between groups. Graph shows similar cumulative incidence for both (HR 0.88, P=.39).
@jamaneurology.comSep 6, 2026, 2:30 PM

đź’¬ Editorial: Among patients with #BranchAtheromatousDisease-related #IschemicStroke, the trial did not show an overall benefit of tirofiban plus aspirin.

ja.ma/3UDTDrh

JAMA Neurology Editorial: 'Tirofiban for Branch Atheromatous Disease—End of the Line or New Opportunity?' authored by Dixon Yang, S. Andrew Josephson, and Hooman Kamel. Published online August 31, 2026.
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