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@labmoons.bsky.socialSep 26, 2026, 9:04 AM

Our #preprint out on @biorxiv-neursci.bsky.social! 🥳🥳
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...

@plosbiology.orgSep 25, 2026, 4:25 PM

A long-standing mystery in #neuroscience is how the length of myelin sheaths are matched to the axons they wrap. Marie Bechler &co show that #oligodendrocytes use Piezo1 to sense axon diameter and locally control sheath elongation 🧪 #NeuroSky buff.ly/9HdgiHt

This image depicts a single oligodendrocyte cell myelinating mixed diameter synthetic axons. The myelin basic protein immunofluorescence image has been colorized by confocal z-plane and modified with edge detection to highlight numerous myelin sheaths of different lengths formed by a single oligodendrocyte.  The longer myelin sheath formed on a larger diameter synthetic axon stands out in blue-green. Image credit: Marie E. Bechler
@plosbiology.orgSep 24, 2026, 7:55 AM

A long-standing mystery in #neuroscience is how the length of myelin sheaths are matched to the axons they wrap. Marie Bechler &co show that #oligodendrocytes use Piezo1 to sense axon diameter and locally control sheath elongation 🧪 #NeuroSky buff.ly/9HdgiHt

This image depicts a single oligodendrocyte cell myelinating mixed diameter synthetic axons. The myelin basic protein immunofluorescence image has been colorized by confocal z-plane and modified with edge detection to highlight numerous myelin sheaths of different lengths formed by a single oligodendrocyte.  The longer myelin sheath formed on a larger diameter synthetic axon stands out in blue-green. Image credit: Marie E. Bechler
@plosbiology.orgSep 22, 2026, 1:00 PM

A long-standing mystery in #neuroscience is how the length of myelin sheaths are matched to the axons they wrap. Marie Bechler &co show that #oligodendrocytes use Piezo1 to sense axon diameter and locally control sheath elongation 🧪 #NeuroSky buff.ly/9HdgiHt

This image depicts a single oligodendrocyte cell myelinating mixed diameter synthetic axons. The myelin basic protein immunofluorescence image has been colorized by confocal z-plane and modified with edge detection to highlight numerous myelin sheaths of different lengths formed by a single oligodendrocyte.  The longer myelin sheath formed on a larger diameter synthetic axon stands out in blue-green. Image credit: Marie E. Bechler
@bcmfromthelabs.bsky.socialSep 10, 2026, 9:10 PM

A. Chandrakantan, HK Lee, B Deneen et al found cellular and molecular players contributing to #pediatricObstructiveSleepApnea #POSA #myelin #oligodendrocytes #Corpuscallosum @bcmhouston.bsky.social @sciencedirect.bsky.social #ExpNeurol www.bcm.edu/news/new-ins...

@gliameeting.bsky.socialSep 8, 2026, 10:40 AM

Research Spotlight 💡

How do oligodendrocytes contribute to age-related cognitive decline? Craig et al. link oligodendrocyte dysfunction and reduced NRF2 expression to changes in myelin, axonal health & cognition.

https://www.nature.com/articles/s41591-026-04608-y

#NetworkGlia #Oligodendrocytes