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@sigtrans-sttt.bsky.socialOct 8, 2026, 6:15 AM

New first-line strategies are needed for metastatic #ColorectalCancer. The APICAL-CRC phase II trial finds promising #antitumor activity and manageable safety with sintilimab plus anlotinib in treatment-naïve patients.

#STTT #OpenAccess: doi.org/10.1038/s413...
#MetastaticCRC #Immunotherapy

Anlotinib plus sintilimab as first-line treatment for patients with advanced colorectal cancer (APICAL-CRC): an open-label, single-arm, phase II trial
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