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@4040rec.bsky.socialOct 7, 2026, 10:48 AM

#pharmaceuticals #SOBI #NICE #Tryngolza #olezarsen #FCStreatment #NICEGuidance #NICEfinaldraftguidance #England #Wales #familialchylomicronaemiasyndrome #triglycerideloweringtreatments #ultrararediseases #inheritedlipiddisorder #hypertriglyceridaemia #Balancestudy #FCScommunity #NHS
zurl.co/7AC7l

@thelancetendo.bsky.socialSep 14, 2026, 11:28 AM

#Hypertriglyceridaemia-induced acute
#pancreatitis is a complex inflammatory disease that
requires immediate medical attention and supportive
care www.thelancet.com/journals/lan...
#triglycerides

#MedSky #EndoSky #CardioSky #GastroSky

Intravenous insulin activates LPL, which increases the clearance of triglycerides from the circulation. Heparin binds to HSPG and releases LPL, leading to a reduction in plasma triglycerides. Heparin also reduces inflammation, oxidative stress, and protects mitochondria in acinar cells of the pancreas. These effects are independent of the triglyceride-lowering effect of heparin. Plasma exchange (plasmapheresis) removes triglycerides directly from circulation. HSPG=heparan sulphate proteoglycan. LPL=lipoprotein lipase.