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@thelancetendo.bsky.socialOct 10, 2026, 12:02 PM

Health-care practitioners need to be aware that #emotional problems are common in #diabetes & often overlooked & follow guidelines that recommend assessing these problems, providing mental health care if needed www.thelancet.com/journals/lan...
#T1D #T2D #GDM #mentalhealth

#EndoSky #PsychSky

@thelancetendo.bsky.socialOct 10, 2026, 11:53 AM

Further research is needed to identify the determinants of #survival and #healthy #ageing among people with type 1 #diabetes, including potential differences between youth-onset and adult-onset disease www.thelancet.com/journals/lan...
#T1D #olderadults #aging

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 10, 2026, 11:42 AM

Increasing evidence indicates that #progression & #complications [of type 2 #diabetes] might be modifiable, but the absence of a core outcome set for disease modification limits trial design & intervention comparison www.thelancet.com/journals/lan...
#disease-modifying therapies

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 10, 2026, 11:35 AM

The global prevalence of #diabetes is rising rapidly, with the steepest increases and greatest unmet need occurring in low-income and middle-income countries.

Read more in this global perspective on the role of #primary #care www.thelancet.com/journals/lan... #T2D #LMICs

#MedSky #EndoSky

@baladocritique.bsky.socialOct 10, 2026, 11:11 AM

“Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.”
Publié ce jour dans @thelancet.com.
#MedSky #EndoSky
www.thelancet.com/journals/lan...

@thelancetendo.bsky.socialOct 9, 2026, 1:15 PM

The pathophysiology of #Hashimoto's #thyroiditis involves an interplay of genetic susceptibility, environmental exposures, & epigenetic modifications that disrupt immune tolerance, promoting T-cell mediated thyroid injury & thyroid autoantibody production
www.thelancet.com/journals/lan...

#EndoSky

@thelancetendo.bsky.socialOct 9, 2026, 8:11 AM

Sten Madsbad & Jens J Holst comment on:
#Petrelintide and the evolving role of #amylin agonism in #obesity thelancet.com/journals/lan...
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 9, 2026, 8:11 AM

#Petrelintide is a novel, long-acting #amylin analogue being developed for long-term treatment of #obesity, leveraging a mechanism of action distinct from incretin-based treatments thelancet.com/journals/lan...
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 9, 2026, 7:08 AM

Shukri F Mohameda & Andre Pascal Kengne comment on:
What #Mauritius teaches us about #diabetes #surveillance thelancet.com/journals/lan...
#T2D #prevalence #OGTT
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 9, 2026, 7:08 AM

#Mauritius is the first country to show a decreasing prevalence of type 2 #diabetes and intermediate hyperglycaemia over time, using the objective, gold standard #OGTT-based diagnostic criteria recommended by the WHO thelancet.com/journals/lan...
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 9, 2026, 6:21 AM

Published in @ebiomedicine.bsky.social

A proteome-based classification of paediatric #adrenocortical #tumours links functional tumour states to clinical outcome and therapeutic vulnerabilities www.thelancet.com/journals/ebi...
#OpenAccess

#MedSky #EndoSky

@endomedia.bsky.socialOct 8, 2026, 7:51 PM

Breaking news: Journal of the @endocrinesociety.bsky.social study found sleeping longer may be linked to diabetic kidney disease. bit.ly/4hE98Ze @endosocjournals.bsky.social #diabetes #JES #EndoSky

@thelancetendo.bsky.socialOct 8, 2026, 5:29 PM

Diagnosis of #Hashimoto's #thyroiditis is based on integrating clinical features, #thyroid function tests, thyroid antibody assessment, and characteristic imaging findings thelancet.com/journals/lan...
primary #hypothyroidism

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 8, 2026, 10:17 AM

Turner syndrome is a sex chromosome abnormality in female individuals characterised by the complete or partial loss of one X chromosome in all or some cells www.thelancet.com/journals/lan...
#Turner syndrome

#MedSky #EndoSky

Traditional genotype–phenotype models of Turner syndrome emphasise haploinsufficiency of individual X-linked genes. However, emerging genomic, epigenomic, transcriptomic, proteomic, and metabolomic data suggest that loss of sex-chromosome dosage produces genome-wide regulatory effects. Loss of Xp, PAR1, and X-inactivation escape genes could perturb epigenetic regulators, transcriptional networks, immune pathways, and metabolic signalling. These disturbances propagate across autosomal gene networks and manifest in a tissue-specific manner, contributing to cardiovascular, skeletal, ovarian, metabolic, immune, neurocognitive, and ageing-related features of Turner syndrome. This network model could help explain the limited genotype–phenotype correlation and the marked clinical variability observed even among individuals with 45,X monosomy.
@thelancetendo.bsky.socialOct 8, 2026, 7:15 AM

Hashimoto's thyroiditis is the most common cause of primary #hypothyroidism in #iodine-sufficient regions and is characterised by immune-mediated injury to thyroid follicular cells www.thelancet.com/journals/lan...
##Hashimoto's #thyroiditis
primary #hypothyroidism

#MedSky #EndoSky

@endocrinenews.bsky.socialOct 7, 2026, 3:46 PM

A recent #JCEMCR article describes a 52yo male who presented with cerebrospinal fluid rhinorrhea and was found to have an invasive, 4.2-cm #pituitary mass with modestly elevated prolactin. When the surgeons resected the tumor, it revealed another. #EndoSky
endocrinenews.endocrine.org/double-troub...

@thelancetendo.bsky.socialOct 7, 2026, 3:39 PM

Although highest shortly after treatment initiation, the risk [of #ketoacidosis with #SGLT2 inhibitors] persists over time and should be evaluated throughout treatment. Patients should be instructed to pause treatment during acute illness and stress thelancet.com/journals/lan...
#T2D #DKA

#EndoSky

@thelancetendo.bsky.socialOct 7, 2026, 12:54 PM

Incidental #adrenal #tumours are uncommon in adults younger than 40 years but increase in frequency with age—the highest incidence occurs in the seventh and eighth decades of life www.thelancet.com/journals/lan...
#MedSky #EndoSky

@thelancetendo.bsky.socialOct 7, 2026, 10:52 AM

Major transformations in #lipid #metabolism & #cardiovascular disease prevention have occurred during the first quarter of the 21st century & have impacted clinical practice. Find out more in this TimeCapsule article www.thelancet.com/journals/lan...
#LDL #cholesterol

#MedSky #EndoSky #CardioSky

@drjwdietrich.bsky.socialOct 7, 2026, 9:51 AM

🧪 🩺 #MedSky @medsky.social Endocrinology #Endosky

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