5/5: SPAE provides a computational framework for investigating cell cycle dynamics, cellular states, and transcriptional heterogeneity in scRNA-seq data. Code available for non-commercial use:
github.com/YaJahn/SPAE
#scRNAseq #CellCycle #ComputationalBiology

Interested in #CellCycle regulation and #DevelopmentalBiology? Sign up for the EMBO Workshop "Cycling towards fate: Cell cycle control in development" in Amsterdam, NL, 7–10 June 2027.

Deadline: 1 February 2027

https://meetings.embo.org/event/27-cell-cycle-control
#EMBOcellCycle #EMBOevents 🧪

Components of an #ESCRT-independent #NuclearEnvelope assembly pathway. New study from Emma M. Sydir, I-Ju Lee, David Pellman @danafarber.bsky.social @harvard.edu and colleagues:
rupress.org/jcb/article/...

#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid

In @jcb.org, Sydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...

#CellCycle #CellDivision #Genetics #Biochemistry

🧬 How do cells ensure their DNA is copied completely and accurately before division? The Boos Lab at @imprs-lm.bsky.social is recruiting a PhD student to study the molecular control of replication origin firing — a key process for maintaining genome stability. Apply now!
#DNAReplication #CellCycle

Sydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...

#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid

Interested in #CellCycle and #Pluripotency? 👇

We found that mouse and human use distinct regulatory regimes for cell-cycle control. Mouse pluripotent systems keep a higher baseline expression of core cell-cycle regulators, whereas human systems show larger oscillatory amplitude with a lower baseline. #Pluripotency #CellCycle

Hey! You can have a look at our new preprint on #CellCycle regulation and #Pluripotency! A little thread 100% human 0% AI slop is coming (bear with me the mistakes). Let's thank first @maulik_nariya, the fantastic postdoc that led this project: www.biorxiv.org/content/10.6...

Spatially ordered zygotic genome activation fulfills embryo quality control. New study from Wenchao Qian, Hui Chen, Hongju Lee, and Matthew C. Good @buenoscience.bsky.social @upenn.edu:
rupress.org/jcb/article/...

#Technology #Development #CellCycle #CellDdivision #CellSignaling