@cp-molcell.bsky.social
Molecular Cell is a Cell Press journal that aims to publish the best papers in molecular biology.
@cp-molcell.bsky.socialOnline Now: 40S ribosome remodeling triggers 18S rRNA U-tailing and DIS3L2-dependent decay Online now:
@cp-molcell.bsky.socialOnline Now: Oligo(uridine) tailing and exonucleolytic decay drive 40S ribosome degradation in response to stress Online now:
@cp-molcell.bsky.socialOnline Now: Mechanistic insights into chromatin modulation by the “orphan” remodeler ATRX Online now:
@cp-molcell.bsky.socialOnline Now: Toward interpretable foundation models for molecular biology Online now:
@cp-molcell.bsky.socialOnline Now: Ribosome remodeling drives translation adaptation during viral infection and cellular stress Online now:
@cp-molcell.bsky.socialOnline Now: A genome-scale adaptation map identifies the FANCM-RMI1/2 complex as an opposing modulator of cell fitness upon BRCA1 or BRCA2 loss Online now:
@cp-molcell.bsky.socialOnline Now: DNASE1L3 maintains homeostatic levels of mitochondrial DNA on the mammalian cell surface Online now:
@cp-molcell.bsky.socialOnline Now: DND1-NANOS3 shapes the PGC transcriptome via a heptanucleotide sequence in mRNA 3′ UTRs Online now:
@cp-molcell.bsky.socialOnline Now: An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal, and inherited genomic events Online now:
@cp-molcell.bsky.socialDDIAS shields vulnerable single-stranded DNA to direct neurogenesis and protect cancer cells
@cp-molcell.bsky.socialAn unexpected role for cyclin E-CDK2 in regulating responses to cancer immunotherapy
@raflynn5.bsky.socialReposted by @cp-molcell.bsky.socialAlmost 1 year to the day, now published @cp-molcell.bsky.social, our report of cell surface DNA + csATAC to detect and study it. Jennifer et al have added many new data including proximity network analysis of csDNA on PBMCs and exciting data from SLE patients.
@benjaminfozzy.bsky.socialReposted by @cp-molcell.bsky.social✍ It's been a journey... Published today in @cp-molcell.bsky.social (www.sciencedirect.com/science/arti...) is the culmination of a lot of work that started over 7 years ago with the observation that the RPA complex could enhance the DUB activity of ZUP1 against K63-linked polyubiquitin chains.
@cp-molcell.bsky.socialHypoxia? NNoT a PROblem!
@cp-molcell.bsky.socialMolecular glue everywhere: Metabolites join the party
@cp-molcell.bsky.socialUbiquitin chain editing promotes p97/VCP-dependent removal of RPA from DNA
@cp-molcell.bsky.socialZNFX1, an immunoregulatory RNA helicase and E3 ubiquitin ligase, assembles into pleiomorphic polymers
@cp-molcell.bsky.socialConserved and divergent mitochondrial assemblies in kinetoplastid parasites
@cp-molcell.bsky.socialLineage-specific innovations expand mitochondrial proteomes in kinetoplastids
@cp-molcell.bsky.socialCaMKII monomers are sufficient for GluN2B binding, co-condensation, and synaptic potentiation
