@jcb.org
Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press @rupress.org
🌐 https://rupress.org/jcb
@jcb.orgChadha, Schmoller et al. follow budding #yeast cell lineages as they adapt their size in response to a nutrient shift. They show that size regulators that seem redundant in steady-state can have specific roles for cell size adaptation. rupress.org/jcb/article/...
@jcb.orgHow cells adapt their membranes to prolonged stress is poorly understood. Williams, Klose, Ernst, and Carvalho @dunnschool.bsky.social show that chronic hyperosmotic stress triggers #LipidDroplet accumulation and a shift toward phosphatidylcholine in budding #yeast. rupress.org/jcb/article/...
@jcb.org📽️ See a short video summary of the study by first authors Tiantian Zhou and Yazhou Liu: youtu.be/tHRCS4JDfjc
@jcb.orgYuanjiao Du, Tiantian Zhou, Yazhou Liu et al. identify the atypical VAP-family protein MOSPD3 as an ER receptor for the lipid-transfer protein ATG2A, anchoring it at ER–phagophore contacts to support #autophagy . rupress.org/jcb/article/...
@jcb.orgA structural model for the autoinhibition of the γ-TuRC-activating CM1 domain. New study by Abir Elfarkouchi, Arthur Vitard, Françoise Ochsenbein @francoizochsenbein.bsky.social @univparissaclay.bsky.social, Paul Conduit @pconduit.bsky.social @ijmonod.bsky.social et al. rupress.org/jcb/article/...
@jcb.orgYou Wu and David J. Reiner @tamu.bsky.social provide in vivo evidence for the long-proposed role of the Ras effector Ral, a small #GTPase, in regulating the metazoan #exocyst complex. rupress.org/jcb/article/...
@jcb.orgHow cells increase energy production to meet the demands of force response is incompletely understood. Dawson, DeMali et al. suggest that the muscle isoform of the glycolytic enzyme phosphofructokinase (PFK) is recruited to #actin, thereby serving this important role. rupress.org/jcb/article/...
@jcb.org📢 Attention #undergraduates, #gradstudents, and early-career #postdocs! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards ✈️ that support your attendance at #CellBio2026 (Dec. 12-15) in San Diego! Apply by October 18 👉 rupress.org/jcb/pages/al...
@jcb.orgOur October issue is here! rupress.org/jcb/issue/22...
The cover shows #Xenopus blastula embryos undergoing zygotic genome activation (ZGA). Top: normal embryo; bottom: inverted embryo.
From Wenchao Qian, Matthew C. Good @buenoscience.bsky.social & colleagues (doi.org/10.1083/jcb....)
@jcb.orgComponents of an #ESCRT-independent #NuclearEnvelope assembly pathway. New study from Emma M. Sydir, I-Ju Lee, David Pellman @danafarber.bsky.social @harvard.edu and colleagues:
rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
@jcb.orgRead two recent JCB papers from the Zhi Hong lab:
"Light-based modulation of astrocytic calcium for regulation of organelle dynamics and morphogenesis" hubs.la/Q04rdw520
"Dynamic interaction of REEP5–MFN1/2 enables mitochondrial hitchhiking on tubular ER" hubs.la/Q04rdwv50
@jcb.org“The monitoring editors are highly professional, thoughtfully synthesizing reviewer comments and providing clear guidance that helped us prioritize our revision efforts.”— Dr. Zhi Hong
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
@pconduit.bsky.socialReposted by @jcb.orgHappy to see our latest work published in @jcb.org. Led by an excellent PhD student, Abir Elfarkouchi, and in collaboration with @francoizochsenbein.bsky.social and co-first author Arthur Vitard, we investigated the structural mechanism of CM1 domain autoinhibition rupress.org/jcb/article/...
@jcb.orgAbir Elfarkouchi, Arthur Vitard, @francoizochsenbein.bsky.social, @pconduit.bsky.social et al. reveal the first structural model for γ-TuRC CM1 domain autoinhibition, which prevents ectopic binding and activation of #microtubule-nucleating γ-tubulin ring complexes. rupress.org/jcb/article/...
@needhibhalla.bsky.socialReposted by @jcb.org“The broader lesson may be that interrogating stress responses by unleashing chemical or genetic catastrophe on the cells tells you what the pathways can do but not necessarily what the cell uses them for.”
@jcb.orgSubtlety is underrated: physiological UPR activation in #meiosis. David Pincus (University of Chicago) and Vladimir Denic @harvardmcb.bsky.social discuss new work by Bartolutti, Brar and colleagues (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
@jcb.orgSydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
@jcb.org📢 Supporting the #nextgeneration of researchers, JCB offers the Hall & Gilula Travel Awards ✈️ that assist #undergraduates, #gradstudents, and early-career #postdocs in attending #CellBio2026 (Dec. 12-15)! Apply by October 18 👉 rupress.org/jcb/pages/al...
@jcb.orgSpotlight: Bartolutti, Brar et al. @berkeleymcb.bsky.social (rupress.org/jcb/article/...) describe how physiological UPR induction drives #gametogenesis in budding #yeast. David Pincus and Vladimir Denic discuss the work: rupress.org/jcb/article/...
@jcb.orgVisualizing the #Golgi apparatus and Golgiphagy in vivo. New study on reporter mouse models developed by Pengwei Zhao, Mengyuan Zhang, Rongbin Ding, Lingling Zhang, Yongjuan Sang, Qiming Sun and colleagues (Zhejiang University):
rupress.org/jcb/article/...
