@jcb.orgMOSPD3 mediates the ER recruitment of ATG2A to promote #autophagy. New study from Yuanjiao Du, Tiantian Zhou, Yazhou Liu, Wei-Ke Ji (Huazhong University of Science and Technology) and colleagues:
rupress.org/jcb/article/...
π½οΈ See video summary by Tiantian Zhou and Yazhou Liu: youtu.be/tHRCS4JDfjc
@adaptaml.bsky.socialExcited to have our lab represented at #CFATG13! π§¬β¨
Carine Joffre delivered an inspiring keynote presentation followed by a great short talk from @laurapoillet.bsky.social on our research!
Thanks to the organizers @cfatg.bsky.social for this fantastic conference!π
#autophagy #leukemia #resistance
@angegross.bsky.socialEnjoying nice Poster Sessions @plantproteostasis.bsky.social Conference in the beautiful city Strasbourg. Excited about @glangin.bsky.social presenting first results from our lab.
#autophagy #plantstress
@timsargeant.bsky.socialHow long do you need to fast to increase autophagy? 24 hours? 48? 72?
The human evidence cannot yet give us a reliable answer.
Dr Sanjna Singh and I separate fact from fiction in our new open-access review:
@timsargeant.bsky.socialHere is our new paper from Dr Sanjna Singh on dietary #protein and #autophagy measured in human blood. It was a negative result, but probably the hardest research I've been involved with. Proud of the study and wonderful collaborators!
@stephanhacker2.bsky.socialInteresting talk by Andrea Arrieche Suarez at #ICBS2026.
She talked about her work on selective #autophagy inhibitors by targeting ATG14L-Beclin interaction to treat ovarian #cancer.
@physrep.bsky.socialInclusion of Tat-#Beclin, an activator of #autophagy, with an endurance #exercise program in aged male mice has additive effects on improvements in physical function and increases in proteins associated with #bioenergetics or acute #inflammation by #proteomics.
doi.org/10.14814/phy...
#Ageing
@sigtrans-sttt.bsky.socialUsing comprehensive #Multiomics analyses, researchers identify PLPP2-mediated phosphatidylethanolamine biosynthesis as a driver of #LiverRegeneration by promoting GLI1 stabilization and #Autophagy while alleviating #ERstress.
@korolchuklab.bsky.social#Autophagy and #mTOR papers from last week in the list below. As always lots of interesting science to be read and enjoyed hot off the press!
Reducing methionine intake activates cellular maintenance processes like autophagy, mirroring the benefits of calorie restriction.
@rupress.orgIn @jcb.org, Yuanjiao Du, Tiantian Zhou, Yazhou Liu et al. identify the atypical VAP-family protein MOSPD3 as an ER receptor for the lipid-transfer protein ATG2A, anchoring it at ERβphagophore contacts to support #autophagy . rupress.org/jcb/article/...
@jcb.orgYuanjiao Du, Tiantian Zhou, Yazhou Liu et al. identify the atypical VAP-family protein MOSPD3 as an ER receptor for the lipid-transfer protein ATG2A, anchoring it at ERβphagophore contacts to support #autophagy . rupress.org/jcb/article/...
@cells-mdpi.bsky.socialβ¨ πππ’ππ§ππ’ππ’π ππ±πππ₯π₯ππ§ππ πππ¬ππ«π―ππ¬ π«πππ¨π π§π’ππ’π¨π§! β¨
π At the #EMBO Workshop on Autophagy in GrenΓ₯, Denmark, #CellsMDPI awarded the Best Poster Prize to Dr. Ann-Christin Borchers (University of Oslo).
π Congratulations, and best wishes for continued success in research!
@biomednews.bsky.socialHere are this weeks top reports on topics such as:
#diabetes
#ECM
#immunity
#autophagy
#exosomes
Comment below with your topic of interest to get more details
@korolchuklab.bsky.social#Autophagy and #mTOR papers published last week, lots of exciting stuff which shouldnβt be missed!
@sigtrans-sttt.bsky.socialmiR-150 fine-tunes stem cell fate through dual control of #SOX2, regulating its mRNA stability and #Autophagy-mediated degradation via the KLHL20βULK1 axis to balance ectodermal and mesodermal lineage commitment.
#STTT #OpenAccess: doi.org/10.1038/s413...
@icag02.bsky.socialNew Aging Research!
A new study explores how autophagy flux changes with age in sex- and cell type-specific ways and its link to reduced physical function in older adults.
ICAG 2027 | Apr 14β15, Tokyo + Hybrid
Website: agingcongress.com
@korolchuklab.bsky.social#Autophagy and #mTOR papers from last week, enjoy!
@biomedicines.bsky.social𧬠Could a cellular βcleanupβ system hold the key to disease and aging? This review explores how chaperone-mediated autophagy maintains protein balance and influences aging, cancer, and immune and neurological diseases. π¬ #Autophagy #Aging
mdpi.com/2227-9059/12...
@molneurodegenadvnc.bsky.socialAs part of our inaugural review series!
#Autophagy-#lysosomal pathway in #neurodegeneration
Samantha R. McDonough, Aditya K. Rao, Jacqueline M. McAleer, Bergan M. Babrowicz, Manu Sharma
@weillcornell.bsky.social
