🔆 #PaperSpotlight:
"The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework"

#PressRelease ⬇️
https://bit.ly/4ycmdPi

#Aging #DNADamage #Senescence #OA #PeerReviewed #Press #DNA #Publishing

The ICCARP Steering Committee is pleased to announce a new collection with JoVE on Aging and Age-Related Diseases.

Submit your research: www.jove.com/topical-coll...

#Ageing #Aging #AgingResearch #Geroscience #Biogerontology #Senescence

📈 #TrendingWithImpact:
The #Research paper, titled "Senescent cells accumulate lipid droplets," was recently #Published in Volume 18.

#PressRelease ⬇️
https://aging-us.net/2026/07/16/senescent-cells-found-to-accumulate-lipid-droplets-across-aging-and-alzheimers-disease/

#Aging #Senescence #OA

Age-related regenerative loss can compromise repair after liver injury.
Hepassocin activates #AMPK via ANXA2–ERK–p90RSK–LKB1 signaling, countering hepatic #Senescence and impaired #Autophagy while supporting regeneration in the aging liver.

#STTT #OpenAccess: doi.org/10.1038/s413...
#Inflammation

🔆 #PaperSpotlight:
A new #Review was published on August 26, titled “Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging.” @ifomresearch.bsky.social

🔗 https://bit.ly/4yWKGs3

#Aging #Quote #Senescence #DNA #Longevity #Gerontology #OA

🎧 Listen to our #PressRelease on the #Review "Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging."

https://bit.ly/4xON0AY

#Aging #Audio #Podcast #SoundCloud #PaperSpotlight #Senescence #DNA #Longevity #OA #Publishing

🎥 #AgingShort:
Abstract #Video about a #Review published in Volume 18, titled "Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging.” @ifomresearch.bsky.social

🔗 https://doi.org/10.18632/aging.206414

#Aging #PaperSpotlight #Senescence #DNA #OA

"Latency" by the Australian figurative artist known as #Senescence
#Death #skull #MementoMori #painting #art

www.instagram.com/senescence_p...

Aging’s Special Collection on Cell Senescence and Rapamycin:

https://www.aging-us.com/special-collections-archive/cell-senescence-and-rapamycin

#aging #senescence #rapamycin #research #science #meded #openaccess #publications

📢 #CallforPapers:
Aging invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi.

📅 Deadline: October 31, 2026

🔗 Details:
https://www.aging-us.com/judith-campisi-commemorative-call-for-papers

#AgingResearch #Publishing

However, against our prediction, #L1 expression did NOT simply make healthy fibroblasts look aged or senescent.
In fact, many transcriptional effects were broadly opposite to signatures of #aging, #senescence (including repression of #SenMayo and #SASP). 4/7

🚨New preprint from the Benayoun lab!🚨
LINE-1 (L1) #retrotransposons become transcribed with #aging and #senescence, and are thought to contribute to #inflammaging. But what actually happens to a healthy, non-senescent human cell when #L1 turns on?
www.biorxiv.org/content/10.6...
A 🧵, 1/7

T cell exhaustion and #Senescence impose distinct barriers to #Cancer #Immunotherapy.

This review explores their molecular hallmarks and emerging immune-rejuvenation strategies for checkpoint blockade and adoptive cell therapies.

#STTT #OpenAccess: doi.org/10.1038/s413...

#Root cortical #senescence: An adaptive mechanism for #drought tolerance in #crops

www.sciencedirect.com/science/arti...

#PlantScience @rootbiologist.bsky.social @rootarchitecture.bsky.social @plant-sci.bsky.social @plantreproevo.bsky.social @plantresearch.bsky.social @plantrootbiology.bsky.social