Researchers reveal α-synuclein as a modulator of synaptobrevin-2 endocytic trafficking & highlight perturbed SNARE protein trafficking as a potential contributor to synaptic dysfunction & neuronal health in #Parkinsons
onlinelibrary.wiley.com/doi/10.1111/...

What Is Parkinson's Disease? Everything Your Family Needs to Know

https://www.neurocurious.com/blog/what-is-parkinsons-disease-everything-your-family-needs-to-know

#Parkinsons #ParkinsonsDisease #BrainHealth #NeuroCurious #Neurology #LatinaHealth #Dopamine #BrainCare #Familia

Researchers reviewed the landscape of potential drug targets relevant to early intervention in biomarker-defined prodromal #Parkinsons & consider which targets are best suited for testing
journals.sagepub.com/doi/10.1177/...

Heading into the weekend with smiles, fun, and connections that bring our Parkinson’s community together! #WPC2026 #Parkinsons #RedThreadProject

When Parkinson’s medicine wears off, everyday movement can become harder. Doctors call this “OFF time”. A new tablet being researched reduced it by about 37 minutes a day on average versus a dummy tablet. It isn’t UK-approved and full results are still needed. #Parkinsons #Solengepras

Dr. @debiaselm.bsky.social & @dgsomucla.bsky.social PhD student Adrian Escobar developed 1st-of-its-kind way to map every protein on the surface of microglia using chemically preserved human brain tissue. Read more: t.co/JwpghL3mze #UCLA #Neuroscience #Parkinsons #Alzheimers

New ASAP-supported research explores dopamine transmission, motivational state, and progressive motor-circuit dysfunction in #Parkinsons disease.

This thread highlights recent preprints from CRN Teams Strick, Edwards, and Wichmann.

From kisses at 2 to WWE at 12. 💙🤼

Tomorrow, Fionn walks for Uncle PaPa, who has Parkinson’s.

🎉 PaPa’s Posse just smashed our $2,500 goal! We’re at $2,905!

THANK YOU! The fight continues. Please donate or share!

walk4pd.org/PapasPosse

#Parkinsons #MovingDayBoston #PapasPosse

Absolutely exquisite floral photography Graham my friend 🌷🤩 #Parkinsons #ForJanet ❤️🥰👍🏼

"Braak stage was not associated with H&Y at death, disease duration, age at death, or brain weight in autopsy-proven #Parkinsons patients. These findings provide evidence that path. α-syn–based staging does not represent a model of clinical progression"
www.neurology.org/doi/10.1212/...

"Braak stage was not associated with H&Y at death, disease duration, age at death, or brain weight in autopsy-proven #Parkinsons patients. These findings provide evidence that path. α-syn–based staging does not represent a model of clinical progression"
www.neurology.org/doi/10.1212/...

Researchers measured key cerebrospinal fluid markers in #Alzheimers, dementia with Lewy bodies, & #Parkinsons via fully-automated assays. They found AD pathology was observed in DLB, & related to worse cognition, but less in PD
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

In a longitudinal analysis of a dual biomarker-positive, de novo #Parkinsons cohort & matched controls, neuropsychiatric symptoms increased in prevalence & co-occurrence over the first decade of disease
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...

Join Caroline M. Tanner at the next Research Spotlight for a look at #Parkinsons prevention and precision medicine.

📅 October 13, 2026 | 🕚 11 AM ET / 4 PM UK

Learn more & register: https://www.worldpdcoalition.org/WPCResearchSpotlight2026

#ParkinsonsResearch

Study by George Tofaris, et al. @ox.ac.uk shows that a distinct population of human #Microglia can selectively remove harmful clumps of the #Parkinsons -causing protein alpha-synuclein from dopamine-producing neurons. Learn More in Science Translational Medicine 👉 www.science.org/doi/10.1126/...

Gain Therapeutics report MDS-UPDRS 3 motor scores demonstrated stability to baseline (no disease progression) among the 12 #Parkinsons patients who completed 12 months of daily oral administration of their GCase activator rexaceract
gaintherapeutics.com/newsroom/pre...

Using data from 294 people with mild-to-moderate #Parkinsons enrolled in the Cincinnati Cohort Biomarker Program, @albertoespay.bsky.social & collaborators find "higher levels of physical activity were associated with slower cognitive & motor progression in PD"
www.neurology.org/doi/10.1212/...

"Among patients with early #Parkinsons, nicotinamide riboside treatment for 52 weeks did not improve clinical outcomes & was associated with worse clinical outcomes than placebo"; At week 52, total MDS-UPDRS⬆️by 2.45 points in the treatment group & ⬇️0.27 points in placebo

The results of the 52 week Phase 3 double-blind, placebo-controlled NOPARK trial of nicotinamide riboside in 410 participants with early #Parkinsons have been published. The "findings do not support nicotinamide riboside as a disease-modifying treatment"
jamanetwork.com/journals/jam...

Our movement is 7 years strong! Let’s all keep fighting for everyone with #CommunicationAccess needs due to #aphasia, #ALS, #autism, #TBI, #Parkinsons, #CerebralPalsy, & other causes. Please help us meet our birthday goal before the end of the day on 10/9! lnk.to/C1hbd7

[Image: A 7-shaped balloon…