@laskerfdn.bsky.social#LaskerLaureate Takehisa Kitazawa says he has “encountered multiple drug discovery challenges” in his career. But failure, Kitazawa reminds us during his 2026 Clinical Medical Award acceptance speech, is a necessary step toward success. 🧪
!["Repeating failure is the best path to success, I believe.” [Takehisa Kitazawa smiles in a gray suit, paired with a quote about failure being the best path to success from his 2026 Lasker Award speech.]](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:rwlgqcdor35eg4ad7fq256dp/bafkreiezd23sidv4eckhjbzpsgc4q45pib5q6yzmrlfofjnk2nqwolxwvu@jpeg)
@laskerfdn.bsky.socialFrom playing with LEGO blocks as a child to riding a bicycle through the Himalayas: During his 2026 Clinical Medical Award acceptance speech, #LaskerLaureate Tomoyuki Igawa shares how challenges outside of research have helped influence him as a scientist.
@fds3rd.bsky.social#Hemophilia A Treatment Pioneers Win Lasker Award
More than a decade of work led to a dual-targeting antibody mimic of a blood-clotting protein to treat hemophilia A. Three scientists received a #LaskerAward for their efforts
#Immunology #Science
@fds.wsocial.eu#Hemophilia A Treatment Pioneers Win Lasker Award
More than a decade of work led to a dual-targeting antibody mimic of a blood-clotting protein to treat hemophilia A. Three scientists received a #LaskerAward for their efforts
#Immunology #Science
@laskerfdn.bsky.socialPresenting the 2026 Basic Medical Award, Lasker jury member Jeffrey Friedman mentions the challenges of living with narcolepsy and congratulates #LaskerAward winners Emmanuel Mignot and Masashi Yanagisawa for their work that has had “a major impact on treatment.” 🧪
@laskerfdn.bsky.social🧪 Read how the 2026 Basic Medical Research #LaskerAward winners identified the brain peptide orexin and elucidated its role in narcolepsy: buff.ly/lNR6NYf
@laskerfdn.bsky.social“The story of how orexin, a neuropeptide that maintains wakefulness, was identified and implicated in narcolepsy is no yawner,” Rita Rubin reports in @JAMA.com.
!["We found the disease, he found a gene, and it turned out to be a receptor on the ligand. It was an amazing convergence,” Masashi Yanagisawa told JAMA. [Portrait of Yanagisawa smiling in glasses and a plaid shirt.]](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:rwlgqcdor35eg4ad7fq256dp/bafkreifop6iszi2tv6ti7rvrwgo2u2bdyhufetdsyenlajwp4mrukbhgnm@png)
@laskerfdn.bsky.socialFor Michael J. Fox, the recognition that comes with receiving the 2026 Public Service #LaskerAward “belongs to a much larger community,” The Michael J. Fox Foundation for Parkinson’s Research reports:
https://ow.ly/QyYR50ZNAhT
!["I share this honor with everyone who works side by side with us: scientists, policymakers, and most of all, the patients and families who give their all to this cause." [Michael J. Fox wearing sunglasses and a white cap, smiling among supporters holding Team Fox signs at the New York City marathon.]](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:rwlgqcdor35eg4ad7fq256dp/bafkreie7favuijdwhhx7ctrckj7z3inhijiv54eh7n4xbcsvgjnw32mpsi@jpeg)
@laskerfdn.bsky.socialAlbert Szent-Györgyi was born #OTD in 1893.
Szent-Györgyi won a Basic Medical Research #LaskerAward in 1954 for the discovery of actomyosin, the essential contractile element of muscle. 🧪 Learn more: http://ow.ly/ChOB50B7X0y
@laskerfdn.bsky.social🧪 Watch Emmanuel Mignot’s & Masashi Yanasigawa’s dobermans and mice with narcolepsy (see mouse in lower right-hand corner).
They won a 2026 #LaskerAward for identifying the brain peptide orexin & discovering that orexin deficiency causes uncontrolled sleep in narcolepsy: https://ow.ly/JECv50ZNtsV
@laskerfdn.bsky.socialRobert Flaumenhaft tells us in the Journal of Clinical Investigation how Factor VIIIa replacement was both a “triumph and tragedy,” and which “inspirational step” ultimately led to a breakthrough in the management of hemophilia A.
@laskerfdn.bsky.socialIn the Journal of Clinical Investigation, Clifford B. Saper congratulates the 2026 Basic Medical Research #LaskerAward winners Emmanuel Mignot and Masashi Yanagisawa for making “a ‘touchdown’ in the game of life that every basic scientist dreams about.”
@drclairepomeroy.bsky.social#ICYMI, our 2026 #LaskerAward winners: Emmanuel Mignot & Masashi Yanagisawa; Kunihiro Hattori, Tomoyuki Igawa, Takehisa Kitazawa; & Michael J. Fox
🧪They exemplify the power of the global enterprise of #ScientificResearch & the benefits when we all work together to improve human health & wellbeing.
@laskerfdn.bsky.social🧪 Here, Flora Peyvandi writes how Kunihiro Hattori, Tomoyuki Igawa, and Takehisa Kitazawa developed a prophylactic therapy for hemophilia A, for which they won a #LaskerAward: buff.ly/GYmrihW
@laskerfdn.bsky.social“The discovery of orexins & their link to narcolepsy became central for understanding sleep–wake regulation itself.” 🧪Sebastiaan Overeem & Birgitte R. Kornum report in @nejm.org on the pivotal roles that #LaskerAward winners Mignot & Yanagisawa had in the discovery of orexin:
buff.ly/T3CPftu
@oddlytruejp.bsky.social🧠 In 1998 Masashi Yanagisawa found orexin, the brain's wakefulness switch, and why narcolepsy strikes.
Pharma then spent 28 years building the opposite: sleeping pills that block it.
He and Emmanuel Mignot just won the 2026 Lasker.
@laskerfdn.bsky.social“Japanese sleep scientist Masashi Yanagisawa and three Japanese researchers who developed a #hemophilia treatment drug at Chugai Pharmaceutical Co. won Lasker Awards in medicine on Wednesday,” Kyodo News Official reports.
共同通信北米３支局 Kyodo News North America #Lasker2026 #LaskerAward 🧪
@laskerfdn.bsky.socialHours before receiving a #LaskerAward, French researcher Emmanuel Mignot—who discovered one of the main molecules involved in sleep regulation—shared with L’Express in an exclusive interview “the behind-the-scenes of his work, and details the revolutions to come in the field." 🧪
@laskerfdn.bsky.socialMichael J. Fox’s “efforts show that celebrity can be used to make a meaningful impact. He did this by becoming an informed advocate who engaged scientists, policymakers, donors, and patients with equal authenticity.” —via Journal of Clinical Investigation
@laskerfdn.bsky.social“This year’s awardees were recognized for their achievements in the discovery of orexin, the development of a novel bispecific antibody, and bringing patients to the forefront of drug discovery,” Drug Discovery News reports about the 2026 #LaskerAward winners.