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@midgardfinance.comOct 8, 2026, 7:45 AM

💉 #pharma #obesity #petrelintide $ZEAL 🇩🇰 $RO 🇨🇭
Petrelintide in type 2 diabetes: 7.4-9.2% weight loss at week 28 vs 2.0% on placebo (#ZUPREME-2, Phase 2, 220 people).
Without diabetes: 7.9-9.8% at the same week. HbA1c fell by up to 0.65 points.
midgardfinance.com/obesity/drugs/petrelintide/

Grouped bar chart of average weight change at week 28 in two phase 2 trials of petrelintide, Zealand Pharma's weekly amylin injection partnered with Roche. Left group, ZUPREME-1 in people without diabetes: placebo -1.7 per cent, the dose that lost least -7.9 per cent, the dose that lost most -9.8 per cent. Right group, ZUPREME-2 in people with type 2 diabetes, topline of 7 October 2026: placebo -2.0 per cent, the dose that lost least -7.4 per cent, the dose that lost most -9.2 per cent. The two groups look almost the same: weight loss in people with diabetes is about half a point smaller. ZUPREME-2 has not named its three doses. Figures are for patients who stayed on treatment.
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