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@sigtrans-sttt.bsky.socialOct 1, 2026, 3:45 PM

miR-150 fine-tunes stem cell fate through dual control of #SOX2, regulating its mRNA stability and #Autophagy-mediated degradation via the KLHL20–ULK1 axis to balance ectodermal and mesodermal lineage commitment.
#STTT #OpenAccess: doi.org/10.1038/s413...

Dual-mode SOX2 regulation by miR-150 via mRNA suppression and autophagy controls stem cell fate
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