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@narjournal.bsky.socialOct 7, 2026, 1:44 AM

13. Regulation and #pharmacological targeting of #RAD51 in cancer - Grundy et al. doi.org/10.1093/narc.... Review article on RAD51, the central recombinase regulated by BRCA2, PALB2 and RAD51 paralogs, linking HR control to #cancerprevention and #therapeuticresistance. 14/18

@narjournal.bsky.socialOct 7, 2026, 1:44 AM

8. #RAD51 recruitment but not replication fork stability associates with PARP inhibitor response... - Talens et al. doi.org/10.1093/narc.... Irradiation-induced RAD51 foci predict #olaparibresponse in the #ovarianPDX cohort, whereas fork protection does not. 9/18

@narjournal.bsky.socialOct 7, 2026, 1:44 AM

1.STN1 upregulation promotes #PARPiresistance in BRCA2-deficient cancer cells via replication fork protection... Laghari et al. #BRCA2 loss, #RAD51 loading, #MRE11 exclusion, #forkprotection, and suppression of ssDNA gaps linked to #PARPi resistance doi.org/10.1093/narc... 2/18