1.STN1 upregulation promotes #PARPiresistance in BRCA2-deficient cancer cells via replication fork protection... Laghari et al. #BRCA2 loss, #RAD51 loading, #MRE11 exclusion, #forkprotection, and suppression of ssDNA gaps linked to #PARPi resistance doi.org/10.1093/narc... 2/18

Coming from a family of sisters, I very much enjoyed telling the story of these 2 #badass sisters, both diagnosed w/a #BRCA2 mutation that drove their early-stage #breastcancer.
#Hereditarycancer happens, but u can manage yr risk! More info in my @fredhutch.org story. #CanSky #HCAW #knowyourrisk

Among women with #BRCA1 or #BRCA2 pathogenic variants, the projected benefit of bilateral salpingo-oophorectomy declined with age but remained present into older age.

ja.ma/3To6iy5

Lynparza is a pill used to treat certain early-stage and metastatic HER2-negative breast cancers with an inherited #BRCA1 or #BRCA2 mutation.

Learn how it works and what to expect: https://bit.ly/3Sal23f

#breastcancer #metastaticbreastcancer #breastcancertreatment

Getting your genetic test results can bring answers — and sometimes more questions.

Learn what your results may mean for your cancer risk and the steps you can take if you test positive for an inherited #breastcancer gene mutation. https://bit.ly/3WC1XVu

#BRCA1 #BRCA2 #CancerRisk #GeneticTesting