Curved joint repair calls for devices that combine anatomical adaptability with regenerative control. This study uses #4Dbioprinting to assemble osteoinductive #Microrobots into deformable devices for guided mineralized matrix regeneration.

Curved joint repair calls for devices that combine anatomical adaptability with regenerative control. This study uses #4Dbioprinting to assemble osteoinductive #Microrobots into deformable devices for guided mineralized matrix regeneration.
Orthodontic mechanical forces activate Piezo1⁺ macrophage–B-cell signaling and pathogenic IgM release, driving systemic #Inflammation, #LiverDysfunction and impaired distal #BoneRepair, while metabolic intervention reverses these effects.