In @jem.org, Steffensen, Bratina, De Zio et al. review emerging strategies to convert immunologically cold tumors into immune-responsive lesions, while highlighting key challenges to clinical translation. rupress.org/jem/article/...

In @jem.org, Steffensen, Bratina, De Zio et al. review emerging strategies to convert immunologically cold tumors into immune-responsive lesions, while highlighting key challenges to clinical translation. rupress.org/jem/article/...
Steffensen, Bratina, De Zio et al. review emerging strategies to convert immunologically cold tumors into immune-responsive lesions, while highlighting key challenges to clinical translation. rupress.org/jem/article/...
To overcome tumor immune evasion, researchers engineered NK cells that target PD-L1, block NKG2A/HLA-E inhibitory signaling, and produce IL15 to improve antitumor activity, survival, and metabolic fitness.
#OpenAccess: doi.org/10.1038/s413...
#TumorImmunology #CellTherapy #ImmunoOncology
Linkoping University (@liu.se) is hiring:
Postdoc in Tumor Immunology and Immunotherapy
Technische Universitat Munchen (@tum.de) is hiring:
PhD position in Tumor Immunology
🔬 Meet Associate Prof. Allan Stensballe, Chair for S1: Immune System, Tumor Immunology and Autoimmune Disease at #ECB2027!
📅 10–12 May 2027 | Online
📣 Abstract deadline: 15 Jan 2027
📝 FREE registration: 5 May 2027
🔗 sciforum.net/event/ECB2027 #TumorImmunology
TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment. New study from Elixabet Bolaños, Ignacio Melero @unav.edu and colleagues:
rupress.org/jem/article/...
Sharing a new data visualization exploring the phenotypic reprogramming of exhausted CD8+ T cells following PD-1 axis blockade.
#TcellExhaustion #CheckpointBlockade #TumorImmunology #CD8Tcells #AntiPD1 #Tpex #ImmuneCheckpoint #CancerImmunotherapy
In @jem.org, Bolaños, Melero et al. @unav.edu show that tumor necrosis factor sensing by cancer cells through TNFR1 sets in motion forms of immunosuppressive protumor #inflammation that mediate escape from immune surveillance against tumors. rupress.org/jem/article/...
Bolaños, Melero et al. @unav.edu show that tumor necrosis factor sensing by cancer cells through TNFR1 sets in motion forms of immunosuppressive protumor #inflammation that mediate escape from immune surveillance against tumors. rupress.org/jem/article/...