@scienceofpd.bsky.socialUsing data from 294 people with mild-to-moderate #Parkinsons enrolled in the Cincinnati Cohort Biomarker Program, @albertoespay.bsky.social & collaborators find "higher levels of physical activity were associated with slower cognitive & motor progression in PD"
www.neurology.org/doi/10.1212/...
@scienceofpd.bsky.social"Among patients with early #Parkinsons, nicotinamide riboside treatment for 52 weeks did not improve clinical outcomes & was associated with worse clinical outcomes than placebo"; At week 52, total MDS-UPDRS⬆️by 2.45 points in the treatment group & ⬇️0.27 points in placebo
@scienceofpd.bsky.socialThe results of the 52 week Phase 3 double-blind, placebo-controlled NOPARK trial of nicotinamide riboside in 410 participants with early #Parkinsons have been published. The "findings do not support nicotinamide riboside as a disease-modifying treatment"
jamanetwork.com/journals/jam...
@communicationfirst.bsky.socialOur movement is 7 years strong! Let’s all keep fighting for everyone with #CommunicationAccess needs due to #aphasia, #ALS, #autism, #TBI, #Parkinsons, #CerebralPalsy, & other causes. Please help us meet our birthday goal before the end of the day on 10/9! lnk.to/C1hbd7
[Image: A 7-shaped balloon…
![[Image: A 7-shaped balloon & the words “We’re SEVEN” within a circle. Set against CommunicationFIRST blue, confetti floats in the background.]](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:rttsf4zrtbea47kiv56ec4vb/bafkreicxbzznoqhi6mnfgo7xueugj2ecbkqnwitvuxdzaxnajsuiyzwuhq@jpeg)
@scienceofpd.bsky.socialNew study starting exploring which #Parkinsons patients are likely to benefit from GLP-1 receptor agonists. The STRAT-GLP1, funded by the Michael J Fox Foundation, aims to develop is a practical stratification tool based on information routinely collected by GPs
www.imperial.ac.uk/news/article...
@scienceofpd.bsky.socialJupiter Neurosciences announces first patient dosed in their randomized, double-blind, placebo-controlled Phase 2a RESET trial (NCT07592767) evaluating safety, pharmacokinetics & biomarkers of JOTROL (formulation of trans-resveratrol) in #Parkinsons
jupiterneurosciences.com/press-releas...
@oxfordbrc.bsky.socialNew research from @ndcnoxford.bsky.social reveals how a specialised group of the brain’s immune cells may help to protect nerve cells in #Parkinsons, raising hopes that new paths to treatments to slow or stop the disease can be identified oxfordbrc.nihr.ac.uk/brain-immune... @medsci.ox.ac.uk
@oldmanrambling.bsky.socialMore #Tulips but today for #ThrowbackThursday and #ColorADay #YellowThu I have some blooms pictured at Emmetts NT gardens in April, during Parkinson's Awareness Month.
#Flowers #Parkinsons #ForJanet
#Bloomscrolling #ECK
#PhotographersOfBluesky
#iPhonePhotography
@jamezfrondeskias.wsocial.euThis is good news for those suffering #parkinsons
The experimental drugs could result in people not getting it.
@togetherforsharon.bsky.socialWhat does Parkinson’s really do to a family?
🎬 Watch
18 years of Parkinson’s. A son who became a caregiver. A family transformed. And a promise to keep her voice alive.
▶️ WATCH: youtu.be/RkWTMNFmUdM
Watch it. Share it. Start a conversation.
#Parkinsons #ParkinsonsAwareness #SharonStory
@scienceofpd.bsky.socialNew research provides single-cell profiling of mitochondrial genomic alterations in pedunculopontine-cholinergic neurons in #Parkinsons, displaying extensive mitochondrial DNA structural disruption dominated by large-scale mitochondrial DNA deletions
academic.oup.com/brain/advanc...
@scienceofpd.bsky.socialDietary l-Arginine supplementation rescues both the MPTP & virally overexpressed mutant α-synuclein models of #Parkinsons. In addition, removing l-Arginine from the diet in both models exacerbated inflammasome activation & worsened pathology & symptoms
@scienceofpd.bsky.socialResearchers screening "nutrients & metabolites" found that l-Arginine inhibits NLRP3 inflammasome assembly in vitro. It binds to the Asp31 site of the NLRP3 protein, blocking its interaction with ASC. L-Arginine levels significantly⬇️in #Parkinsons serum
www.nature.com/articles/s42...
@worldpdcongress.bsky.social🔬 Are biomarkers ready for clinical practice? WPC 2026’s Controversy Session tackled the debate. #WPC2026 #Parkinsons #ParkinsonResearch #Biomarkers
@asapresearch.parkinsonsroadmap.orgWe’re pleased to welcome Alberto Ascherio, MD, DrPH; Russ Altman, MD, PhD; and Walter Koroshetz, MD, to ASAP’s Scientific Advisory Board.
Their perspectives augment the board's expertise as ASAP’s work continues to evolve and advance collaborative #Parkinsons research.
@scienceofpd.bsky.socialCerevance report that the high dose of Solengepras (150 mg) achieved the primary endpoint - reducing average daily OFF time by 0.61 hours vs placebo at Week 12 (p=0.0350; with benefit seen at week 2) - in their Phase 3 ARISE study in #Parkinsons
www.cerevance.com/media/cereva...
@naccsuk.bsky.social🧠 New Clinical Guideline for Perioperative Care of People with Parkinson’s Disease out today
Covers:
Time-critical Parkinson’s meds
Perioperative planning
Important resource for anaesthetists and periop team
Read the guideline via CPOC zurl.co/pTO8v
#Neuroanaesthesia #Parkinsons #Periop Care
@jmlnewsus.bsky.social🕯️ DENNIS HASKINS UPDATE
The death certificate for the actor known as Principal Belding on “Saved by the Bell” lists Parkinson’s disease as his immediate cause of death.
Haskins, 75, had kept his diagnosis private.
@bloodraynes.bsky.socialBeautifully taken and presented my friend 😍 #ForJanet ❤️ #Parkinsons
@bloodraynes.bsky.socialGorgeous Graham my friend 🤩💛👌🏼
#ForJanet #Parkinsons ❤️❤️