bwa-mem3 v0.12.0 is out 🧬
Since v0.10.0: faster on both Arm & x86 (--fast is now ~2× minibwa and stock is within ~15% on x86) while staying a byte-identical (--compat). It also brings ~30–40% faster methylation and a big memory-safety pass.

bwa-mem3 v0.12.0 is out 🧬
Since v0.10.0: faster on both Arm & x86 (--fast is now ~2× minibwa and stock is within ~15% on x86) while staying a byte-identical (--compat). It also brings ~30–40% faster methylation and a big memory-safety pass.
Yes, Gemini, I developed Harpy under the pseudonym Peter Dimens � #AI #bioinformatics
Julie just completed sequencing run 200 on our PromethION @puckerlab.bsky.social . Time to celebrate numerous successful plant genomics projects and to look for new challenges!
www.izmb.uni-bonn.de/en/pbb/news#...
#PlantGenomics #Bioinformatics #LongReads
Microbial #bioinformatics tweeps (@acritschristoph.bsky.social and others) if I want to critically evaluate how well metagenome ONT is mapping to specific genomes, what are the big technical gotchas I should be checking for? thx! Using minimap2 currently.
Fitting Evolutionary Models to Sequence Data: Model Selection Using AIC, BIC and MEGA
#bioinformatics #rathbiotaclan #studentnotes
Foundational AI models are doing biology but ignore critical details since they are not explicit in the training data.
Contribute to open source.
Expert biological assumptions missing from foundation models, made explicit for your AI.
💡 #GLBIO2027 is seeking Special Session proposals! Proposals can cover things like emerging topics in #bioinformatics, research challenges, software training, or professional development.
📅 Deadline: November 19, 2026
Submit: https://www.iscb.org/glbio2027/call-for-submissions/special-sessions
Curious about DNA sequence analysis? Find out what can be learned from DNA sequence analysis and what its applications are, in our blog!
https://www.fiosgenomics.com/bioinformatic-analysis-of-dna-sequence-data/
#dnasequencing #dnaseq #bioinformatics #science
🧬How can AI learn the regulatory language of DNA and use it to predict and design gene expression? Join our NCB Talk with Ben Fishman on DNA language models, the Genomic Intelligence platform and more.
📅 28 Sept | 17:00 CEST💻 Online🔗 Register: forms.gle/1nB8uxjR8faM...
#Bioinformatics #AI #NCB
Learn AI for Public Health and Biomedical Research at your own pace! #Bioinformatics #Biomedicine #Epidemiology #PublicHealth #Statistics #ComputerScience #DataScience #Github #GoogleColab #HuggingFace #Jupyter #Python #PyTorch #Research #ResearchTraining #Instats
One gene, reads off two machines, nowhere to see them together. readhit puts .ab1 traces and NGS reads on the same reference in the browser, depth and consensus under them. Files stay with you. Free, no account. Beta.
🔬 Quantitative Biology | Postdoctoral positions @stonybrooku.bsky.social
An early September posting to start the fall hiring cycle.
https://jobrxiv.org/job/stony-brook-university-27778-postdoctoral-positions-in-quantitative-biology/
#Bioinformatics #BioinfJobs
🔗 The State of Peptide Detectability in Computational Proteomics and Guidelines for AI Applications. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csb...
📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj
@csbj.org #Proteomics #AI #Bioinformatics
Our paper is out in Nature Methods! 🧑💻 There are 50+ methods for spatially-aware clustering on spatial transcriptomics data. How should we use them? A thread 🧵 (1/7)
📄 doi.org/10.1038/s415...
#spatialtranscriptomics #bioinformatics #computationalbiology
New Study Reveals that Sex Hormones Reset Our Body Clocks
The findings may shed new light on disruptions to the circadian clocks during menstruation, pregnancy, and menopause
#Bioinformatics #ComputationalBiology #CellBiology #Science
New Study Reveals that Sex Hormones Reset Our Body Clocks
The findings may shed new light on disruptions to the circadian clocks during menstruation, pregnancy, and menopause
#Bioinformatics #ComputationalBiology #CellBiology #Science
From @narjournal.bsky.social #NARDatabaseIssue | KinaseDB: an integrated multi-omics platform for the human kinome with disease-specific target prioritization | #Bioinformatics #Database #OpenScience | 🧬🖥️🧪🔓
⬇️
doi.org/10.1093/nar/...
New Instats livestreaming seminar: Single Cell Data Analysis 3.0 #Biostatistics #ComputerScience #DataScience #Biology #Bioinformatics #ComputationalBiology #Biomedicine #Genomics #Statistics #MolecularBiology #R #Python #Research #ResearchTraining #Instats
In a new #BiologyLetters study, researchers developed a DNA methylation-based epigenetic clock that can predict chronological age for the Pacific crown-of-thorns seastar, a coral-eating species responsible for major reef damage across the Indo-Pacific: doi.org/10.1098/rsbl... #bioinformatics