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@aspenbio.bsky.socialSep 11, 2026, 5:15 PM

Give us 10 minutes and we'll show you how Digital Transformation with AI and Automation can change your drug discovery operations.

bit.ly/4blEtN6

#DrugDiscovery #DigitalTransformation #AI #automation.

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@analyticalsci.bsky.socialSep 11, 2026, 2:20 PM

🔬 More data, more complex models, more automation. How is analytical science keeping up?

Madeline M. Farley of SLAS explores how these shifts are changing drug discovery and helping researchers focus on what matters: the insights.

🔗 https://ow.ly/VtFZ50ZGzhY

#DrugDiscovery

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@pwk2024.bsky.socialSep 11, 2026, 2:09 PM

A most excellent molecule with which to conclude the week #SynChem #BB #MedChem #DrugDesign #DrugDiscovery #cheminformatics #chemsky 🧪
enaminestore.com/catalog/EN30...

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@stephanhacker2.bsky.socialSep 11, 2026, 8:19 AM

Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.

They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using coPELs.

pubs.rsc.org/sc/article/d...

#ChemSky #ChemBio #DrugDiscovery #CovalentInhibitor

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@thebabaklab.bsky.socialSep 10, 2026, 8:03 PM

Researchers developed ProteinTalks, an AI-based virtual cell model that predicts how cancer cells respond to drugs by tracking changes in their proteins over time.

Link in the comments 👇

#ScientificWednesdays #Proteomics #AI #DrugDiscovery #CancerResearch

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@lunaibioworks.comSep 10, 2026, 5:10 PM

Our subsidiary, BioSymetrics, has initiated a collaboration focused on CDKL5 Deficiency Disorder (CDD), a rare genetic epilepsy. It is working with BrainStorm Therapeutics and academic collaborators to discover and validate therapeutic candidates. #CDKL5 #RareEpilepsy #DrugDiscovery

Building better models for CDKL5 deficiency disorder discovery and translational validation – BioSymetrics/Lunai Bioworks
@markfortner.bsky.socialSep 10, 2026, 4:25 PM

Researching your next drug discovery position? Pharm2Market tracks regional hub updates, leadership teams, networking events and pipelines to give you an edge in your job search.

beta.pharm2market.app/

#BiotechJobs #LifeSciences #DrugDiscovery #BiotechCareers #Pharm2Market

@aspenbio.bsky.socialSep 10, 2026, 4:10 PM

Researching your next drug discovery position? Pharm2Market tracks regional hub updates, leadership teams, networking events and pipelines to give you an edge in your job search.

beta.pharm2market.app/

#BiotechJobs #LifeSciences #DrugDiscovery #BiotechCareers #Pharm2Market

@sigma1europe.bsky.socialSep 10, 2026, 3:46 PM

🧠 SIGMA-1 EUROPE at the 3rd Drug Discovery Conference!

📍 Riga, Latvia | 24–25 Sept 2026

CNS Pharmacology session with Liga Zvejniece, Tangui Maurice & Karolina Pytka.

🔗 sigma1europe.eu

#SIGMA1EUROPE #DrugDiscovery

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@fiosgenomics.bsky.socialSep 10, 2026, 3:30 PM

Want to quickly learn what bioinformatics analyses are & what their applications are? This blog has all the answers: https://www.fiosgenomics.com/bioinformatics-analyses

#bioinformatics #datascience #lifesciences #drugdiscovery #drugdevelopment

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@informaq.bsky.socialSep 9, 2026, 11:09 PM

Cleveland Clinic, RIKEN, and IBM achieved a 12,635-atom protein simulation on quantum computers—the largest quantum-enabled simulation to date. Their automated workflow improved accuracy in binding energy calculations and reduces computational bottlenecks.

#QuantumSimulation #DrugDiscovery #News

@camposvet.bsky.socialSep 9, 2026, 8:20 PM

A great collaborative effort involving UFRGS, UC San Diego, and Feevale University, now published in Bioorganic Chemistry.

The article is available at doi.org/10.1016/j.bi...

#SARSCoV2 #Antiviral #DrugDiscovery #Mpro #MedicinalChemistry #Virology #UFRGS #BioorganicChemistry #Pesquisa #Ciência 5/5

@midwestavidd.bsky.socialSep 9, 2026, 7:17 PM

A new compound developed by
@midwestavidd.bsky.social and published in @natcomms.nature.com is more than 100 times more potent than previously reported Ebola entry inhibitors and shows strong protection in a preclinical model. #antiviral #drugdiscovery

med.umn.edu/news/researc...

@martinvoegele.bsky.socialSep 9, 2026, 5:32 PM

Now published: We used FEP to classify integrin-binding ligands as "opening" or "closing" which can help design safe small-molecule inhibitors as potential new therapeutics.
doi.org/10.1021/jacs...

#Science #Integrin #DrugDiscovery #CompChem 👨‍💻🧪⚗

A Table of Contents (TOC) graphic illustrating the conformational preference classification of integrin-binding ligands. The left panel shows a thermodynamic cycle where a green ligand binds to a blue "closed integrin" with a free energy of Delta-G closed, or to an orange "open integrin" with a free energy of Delta-G open. A horizontal arrow with a question mark represents the conformational transition between the ligand-bound states, governed by the difference of binding affinities to the respective states. The right panel features a scatter plot ranking ligands along an energy axis from -50 to -10 kcal/mol. A dashed vertical boundary at roughly -18 kcal/mol separates the molecules into two distinct groups based on their conformational impact: "opening ligands" depicted as orange circles at lower energy values, and "closing ligands" depicted as blue squares at higher energy values.
@markfortner.bsky.socialSep 9, 2026, 5:30 PM

Give us 10 minutes and we'll show you how Digital Transformation with AI and Automation can change your drug discovery operations.

bit.ly/4blEtN6

#DrugDiscovery #DigitalTransformation #AI #automation.

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@aspenbio.bsky.socialSep 9, 2026, 5:15 PM

Give us 10 minutes and we'll show you how Digital Transformation with AI and Automation can change your drug discovery operations.

bit.ly/4blEtN6

#DrugDiscovery #DigitalTransformation #AI #automation.

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@piellab.bsky.socialSep 9, 2026, 2:02 PM

We found the uncultivated bacterium producing the anticancer drug candidate peloruside A and hiding in an NZ sponge!
It uses a new biochemical trick in complex polyketide biosynthesis.
Congrats Amy, our Victoria University NZ collaborators, and the whole team!
#DrugDiscovery

@medinadiscovery.bsky.socialSep 9, 2026, 1:36 PM

GC ADDA H3D Foundation #RAFIKI #EUOPENSCREEN #DrugDiscovery #NaturalProducts #GlobalHealth #AfricaScience #ResearchTraining #EarlyCareerResearchers

@annualreviews.bsky.socialSep 9, 2026, 12:48 PM

Tomorrow's breakthrough treatments may come from drugs we use now. How is AI using genomics and multiomics data to support drug discovery?

🔗 Freely available thanks to S2O: arevie.ws/45wyEca
✨New to our AI, Machine Learning, and Society collection

#MachineLearning #DrugDiscovery

Figure from the article depicting the process of how to repurpose drugs.
@fiosgenomics.bsky.socialSep 9, 2026, 10:50 AM

Not sure about the steps involved in the Preclinical Phase of drug development? This video explains what happens at each stage, from #drugdiscovery to #toxicology! ▶️
https://youtu.be/5Z5jh02KxkY?feature=shared
#preclinicalresearch #drugdevelopment #bioinformatics

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