Molecular Architecture of the Human GCN1-ABCF3 Ribosome Collision Sensor www.biorxiv.org/content/10.64898/2026.09.19.752920v1 #cryoEM

Molecular architecture responsible for specific inhibition of oncogenic PI3Kα mutants by RLY-2608 and STX-478 pubmed.ncbi.nlm.nih.gov/42764855/ #cryoEM

The pod components of the Shigella T3SS sorting platform accommodate multiple copies of Spa33 (SctQ) pubmed.ncbi.nlm.nih.gov/42766667/ #cryoEM

SMALP Network
@smalp.bsky.social
🧬 Latest Nanodisc News:
Join researchers on Dec 1 @ Membrane Protein Conference to discuss structures, lipid interactions.
⚡ Use code mpc30 for 30%. Read issue & register: preview.mailerlite.io/preview/3650...
#MembraneProteins #Biophysics #StructuralBiology #CryoEM

Structural elucidation of the herpesvirus replication machinery: Cryo-EM insights into helicase-primase complex assembly and mechanisms of antiviral inhibition pubmed.ncbi.nlm.nih.gov/42764902/ #cryoEM

#CryoET and 3D image analysis reveals liposome size, shape, lamellarity, and drug encapsulation. This tomogram of liposomal doxorubicin particles was collected with the Glacios Cryo-TEM and segmented with Amira Software. Chat with our #cryoEM team here: ter.li/gdpxg0ts

Commentary beyond the ATP site: Cryo-EM views of allosteric PI3Kα inhibition pubmed.ncbi.nlm.nih.gov/42764908/ #cryoEM

Monovalent cations differentially regulate the activity of eukaryotic fluoride channels and impact fluoride resistance pubmed.ncbi.nlm.nih.gov/42766647/ #cryoEM

SURFER is a lightweight, GPU-accelerated extension for UCSF ChimeraX that enables rapid semantic differentiation of membrane or membrane-mimic density from macromolecular signal #CryoEM #Segmentation #Membrane doi.org/10.1107/S205...

Co-authors @merylhaas.bsky.social, @danielhurdiss.bsky.social from @utrechtvirology.bsky.social and others show that the norovirus  NS3 protein forms an RNA-engaging molecular motor that may transport viral RNA during infection. #Virology #CryoEM

http://dlvr.it/TVbP01

MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosa pubmed.ncbi.nlm.nih.gov/42766672/ #cryoEM

The teneurin TEN-1 and its ligand LRON-11 support microbiota-induced neuroprotection and mechanosensory function in C. elegans pubmed.ncbi.nlm.nih.gov/42767219/ #cryoEM

Excited to share that our norovirus NS3 study is now online in Nature Communications! 🎉

These enzymes, found across an entire order of RNA viruses, have long been molecular motors in search of a function. We think we’ve uncovered their role. (🧵)

www.nature.com/articles/s41...

#virology #cryoEM

Cryo-EM reveals patient- versus organ-specific structural diversity and bound ligands in λ6 light chain amyloids pubmed.ncbi.nlm.nih.gov/42760916/ #cryoEM

The fall semester has started. See our next #CryoEM Current Practices Webinar with Dong Wang from UCSD, speaking on "Structural basis of transcription recognition of expanded genetic alphabets" 9/24/2026 at 12 PM ET / 9AM PT

Registration here:
us02web.zoom.us/webinar/regi...

Rewriting the genome: harnessing R2 retrotransposons for precise DNA insertion pubmed.ncbi.nlm.nih.gov/42761512/ #cryoEM

High-speed atomic force microscopy of membrane proteins: From dynamic imaging to integrative structural biology pubmed.ncbi.nlm.nih.gov/42762809/ #cryoEM

Structure of the MurA-LpxC enzyme complex in modulating peptidoglycan and lipopolysaccharide biosynthesis pubmed.ncbi.nlm.nih.gov/42762934/ #cryoEM

Ionic Gating of Liquid-Crystal-Like Pteridine Assemblies Enables Tunable Light Scattering pubmed.ncbi.nlm.nih.gov/42755174/ #cryoEM

Cryo-EM structure of a 95-base-pair double-stranded DNA minicircle at 5.3 Å resolution pubmed.ncbi.nlm.nih.gov/42755369/ #cryoEM